SF3B2 产品
(Splicing Factor 3b, Subunit 2, 145kDa (SF3B2))
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This gene encodes subunit 2 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 2 associates with pre-mRNA upstream of the branch site at the anchoring site. Subunit 2 also interacts directly with subunit 4 of the splicing factor 3b complex. Subunit 2 is a highly hydrophilic protein with a proline-rich N-terminus and a glutamate-rich stretch in the C-terminus. [provided by RefSeq, Jul 2008].
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Featured SF3B2 Categories
Recommended SF3B2 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, IHC (p)
Validations
- (6)
Cat. No.
ABIN564766
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (12)
Cat. No.
ABIN6147666
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
IHC, IF
Validations
- (4)
Cat. No.
ABIN7261828
Quantity
200 μL
Datasheet
Datasheet
Recommended SF3B2 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6207545
Quantity
96 tests
Datasheet
Datasheet
Recommended SF3B2 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1319711
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1319713
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3095477
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our SF3B2 Products
: "Cyclin-dependent kinase 1 (CDK1) and CDK2 have opposing roles in regulating interactions of splicing factor 3B1 with chromatin." in: The Journal of biological chemistry, Vol. 293, Issue 26, pp. 10220-10234, (2018) (PubMed).: "PHF5A Epigenetically Inhibits Apoptosis to Promote Breast Cancer Progression." in: Cancer research, Vol. 78, Issue 12, pp. 3190-3206, (2018) (PubMed).
: "PRMT9 is a type II methyltransferase that methylates the splicing factor SAP145." in: Nature communications, Vol. 6, pp. 6428, (2015) (PubMed).
: "The core spliceosome as target and effector of non-canonical ATM signalling." in: Nature, Vol. 523, Issue 7558, pp. 53-8, (2015) (PubMed).
Synonyms and alternative names related to SF3B2
splicing factor 3b, subunit 2 (Sf3b2), splicing factor 3b subunit 2 (SF3B2), splicing factor 3B subunit 2 (LOC714747), splicing factor 3b subunit 2 L homeolog (sf3b2.L), splicing factor 3b subunit 2 (sf3b2), 145kDa, 2610311M13Rik, 2810441F20Rik, B230398H18Rik, cus1, Cus1, SAP145, sap145, SF3b1, SF3B2, SF3b145, sf3b145, SF3B145, SF3b150, sf3b150Protein level used designations for SF3B2
- splicing factor 3B subunit 2
- splicing factor 3b, subunit 2, 145kDa
- splicing factor 3B subunit 2-like
- SAP 145
- pre-mRNA splicing factor SF3b 145 kDa subunit
- pre-mRNA-splicing factor SF3b 145 kDa subunit
- spliceosome associated protein 145
- spliceosome-associated protein 145
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