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XRCC4 抗体 (Middle Region)

XRCC4 适用: 人, 大鼠, 小鼠, 斑马鱼, Cow, 豚鼠, 马, 犬, 兔, Saccharomyces cerevisiae WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2778273
发货至: 中国
  • 抗原 See all XRCC4 抗体
    XRCC4 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 4 (XRCC4))
    抗原表位
    • 15
    • 8
    • 7
    • 6
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    人, 大鼠, 小鼠, 斑马鱼, Cow, 豚鼠, 马, 犬, 兔, Saccharomyces cerevisiae
    宿主
    • 62
    • 5
    克隆类型
    • 64
    • 3
    多克隆
    标记
    • 29
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This XRCC4 antibody is un-conjugated
    应用范围
    • 48
    • 23
    • 13
    • 13
    • 10
    • 8
    • 8
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    LQKENERLLR DWNDVQGRFE KCVSAKEALE TDLYKRFILV LNEKKTKIRS
    预测反应
    Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 92%, Rat: 92%, Yeast: 77%, Zebrafish: 85%
    产品特性
    This is a rabbit polyclonal antibody against XRCC4. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human XRCC4
    Top Product
    Discover our top product XRCC4 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 336 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    XRCC4 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 4 (XRCC4))
    别名
    XRCC4 (XRCC4 产品)
    别名
    zgc:73312 antibody, MGC81443 antibody, homolog of human DNA ligase iv-binding protein XRCC4 antibody, 2310057B22Rik antibody, AW413319 antibody, AW545101 antibody, X-ray repair cross complementing 4 antibody, X-ray repair complementing defective repair in Chinese hamster cells 4 antibody, X-ray repair complementing defective repair in Chinese hamster cells 4 L homeolog antibody, DNA ligase IV-binding protein antibody, XRCC4 antibody, xrcc4 antibody, xrcc4.L antibody, Xrcc4 antibody
    背景
    XRCC4 functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. The non-homologous end-joining pathway is required both for normal development and for suppression of tumors. This gene functionally complements XR-1 Chinese hamster ovary cell mutant, which is impaired in DNA double-strand breaks produced by ionizing radiation and restriction enzymes.The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. The non-homologous end-joining pathway is required both for normal development and for suppression of tumors. This gene functionally complements XR-1 Chinese hamster ovary cell mutant, which is impaired in DNA double-strand breaks produced by ionizing radiation and restriction enzymes. This gene contains 8 exons, and alternative transcription initiation and alternative splicing generates several transcript variants.
    Alias Symbols: -
    Protein Interaction Partner: BIN1, FAM9B, ASTE1, XRCC4, LIG4, PNKP, PRKDC, CSNK2A1, VPS41, NUDT21, CWC27, DENR, USP7, SRP54, DDX5, APTX, ERG, SUMO2, UBC, CALM1, XRCC5, XRCC6, SETMAR, AHNAK, CAAP1, IFFO1, APLF, CHD3, NHEJ1, VIM, GZMB, ACTN1, NBN,
    Protein Size: 336
    分子量
    38 kDa
    基因ID
    7518
    NCBI登录号
    NM_022406, NP_071801
    UniProt
    Q13426
    途径
    DNA Damage Repair, Production of Molecular Mediator of Immune Response
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