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XRCC4 抗体

(X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 4 (XRCC4))
The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. The non-homologous end-joining pathway is required both for normal development and for suppression of tumors. This gene functionally complements XR-1 Chinese hamster ovary cell mutant, which is impaired in DNA double-strand breaks produced by ionizing radiation and restriction enzymes. Alternative transcription initiation and alternative splicing generates several transcript variants. [provided by RefSeq, Sep 2008].
XRCC4 抗体  (AA 1-336) XRCC4 抗体  (AA 1-336) XRCC4 抗体 (AA 1-336) (ABIN3022382)

XRCC4 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

XRCC4 抗体  (AA 1-336) XRCC4 抗体  (AA 1-336) XRCC4 抗体 (AA 1-336) (ABIN1327721)

XRCC4 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Polyclonal unconjugated

XRCC4 抗体  (C-Term) XRCC4 抗体  (C-Term) XRCC4 抗体 (C-Term) (ABIN2856695)

XRCC4 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

XRCC4 抗体 by 适用

Find XRCC4 抗体 for a variety of species such as anti-Human XRCC4, anti-Rat XRCC4, anti-Mouse XRCC4. The species listed below are among those available. Click on a link to go to the corresponding products.

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Find XRCC4 抗体 validated for a specific application such as WB, ELISA, IF (cc), IF (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

XRCC4 抗体 by 抗体来源

Find XRCC4 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

XRCC4 抗体 by 抗原表位

Find XRCC4 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

XRCC4 抗体 by 克隆形成能力

Find available monoclonal or polyclonal XRCC4 抗体. Click on a link to go to the corresponding products.

XRCC4 抗体 by 克隆

Find XRCC4 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

XRCC4 抗体 by 标记

Find XRCC4 抗体 with a specific conjugate such as Biotin, Alexa Fluor 488, Alexa Fluor 555. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular XRCC4 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (2)
  • (7)
Cat. No. ABIN3022382
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p)
Validations
  • (1)
  • (5)
Cat. No. ABIN1327721
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p), ICC
Validations
  • (2)
  • (3)
Cat. No. ABIN2856695
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC, IF
Validations
  • (4)
Cat. No. ABIN7259376
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IP, IHC (p)
Validations
  • (3)
Cat. No. ABIN7250143
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (3)
Cat. No. ABIN521432
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Rat
Application WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (2)
Cat. No. ABIN1386856
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IP
Validations
  • (2)
Cat. No. ABIN7189364
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7245728
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (2)
Cat. No. ABIN3181156
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN7185671
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (1)
Cat. No. ABIN7150305
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN2889295
Quantity 100 μL
Datasheet Datasheet
Reactivity Bat, Cow, Guinea Pig, Horse, Human, Monkey, Pig, Zebrafish (Danio rerio)
Application WB
Validations
  • (1)
Cat. No. ABIN6742430
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC
Validations
  • (3)
Cat. No. ABIN967265
Quantity 0.1 mg
Datasheet Datasheet

Latest Publications for our XRCC4 抗体

Zhang, Chang, Sun, Chen, Yang, Tang, Jing, Kang, He, Wu, Wei, Wang, Xu, Zhu, Shen, Zeng, Wang, Liu, Zhang, Mao, Jiang, Sun: "Histone H3K27 methylation modulates the dynamics of FANCD2 on chromatin to facilitate NHEJ and genome stability." in: Journal of cell science, Vol. 131, Issue 12, (2018) (PubMed).

Wang, Sun, Zhu, Sun, Ma, Wang, Lu, Chen, Xu: "Quantitative proteomic analysis revealed changes in protein synthesis and mitochondrial functions after acute DNA damage in mouse neural stem cells." in: Neuroscience letters, Vol. 653, pp. 355-361, (2018) (PubMed).

Chakraborty, Tapryal, Venkova, Horikoshi, Pandita, Sarker, Sarkar, Pandita, Hazra: "Classical non-homologous end-joining pathway utilizes nascent RNA for error-free double-strand break repair of transcribed genes." in: Nature communications, Vol. 7, pp. 13049, (2018) (PubMed).

Li, Zhang, Chen, Guo, Zhang, Tang, Xu, Zhang, Tao, Wang, Jiang, Sun, Mao: "Impaired DNA double-strand break repair contributes to the age-associated rise of genomic instability in humans." in: Cell death and differentiation, Vol. 23, Issue 11, pp. 1765-1777, (2017) (PubMed).

Zhu, Fisher, Bessho, Peng: "Protein phosphatase 1 and phosphatase 1 nuclear targeting subunit-dependent regulation of DNA-dependent protein kinase and non-homologous end joining." in: Nucleic acids research, Vol. 45, Issue 18, pp. 10583-10594, (2017) (PubMed).

van Sluis, McStay: "A localized nucleolar DNA damage response facilitates recruitment of the homology-directed repair machinery independent of cell cycle stage." in: Genes & development, Vol. 29, Issue 11, pp. 1151-63, (2015) (PubMed).

Reid, Keegan, Leo-Macias, Watanabe, Strande, Chang, Oksuz, Fenyo, Lieber, Ramsden, Rothenberg: "Organization and dynamics of the nonhomologous end-joining machinery during DNA double-strand break repair." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 20, pp. E2575-84, (2015) (PubMed).

Dong, Wang, Wang, Zhang, Zhu, Gao, Yang, Qin, Liang, Chen, Deng, Ning, Liang, Gao, Xu: "A stress-induced cellular aging model with postnatal neural stem cells." in: Cell death & disease, Vol. 5, pp. e1116, (2014) (PubMed).

Enervald, Du, Visnes, Björkman, Lindgren, Wincent, Borck, Colleaux, Cormier-Daire, van Gent, Pie, Puisac, de Miranda, Kracker, Hammarström, de Villartay, Durandy, Schoumans, Ström, Pan-Hammarström: "A regulatory role for the cohesin loader NIPBL in nonhomologous end joining during immunoglobulin class switch recombination." in: The Journal of experimental medicine, Vol. 210, Issue 12, pp. 2503-13, (2013) (PubMed).

Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).

Aliases for XRCC4 抗体

X-ray repair cross complementing 4 (XRCC4) 抗体
X-ray repair complementing defective repair in Chinese hamster cells 4 (xrcc4) 抗体
X-ray repair complementing defective repair in Chinese hamster cells 4 L homeolog (xrcc4.L) 抗体
DNA ligase IV-binding protein (XRCC4) 抗体
X-ray repair complementing defective repair in Chinese hamster cells 4 (Xrcc4) 抗体
X-ray repair cross complementing 4 (Xrcc4) 抗体
2310057B22Rik 抗体
AW413319 抗体
AW545101 抗体
homolog of human DNA ligase iv-binding protein XRCC4 抗体
MGC81443 抗体
zgc:73312 抗体
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