电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

PPARG 抗体 (N-Term)

PPARG 适用: 人, 犬, Pig WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2777644
发货至: 中国
  • 抗原 See all PPARG 抗体
    PPARG (Peroxisome Proliferator-Activated Receptor gamma (PPARG))
    抗原表位
    • 21
    • 18
    • 16
    • 16
    • 16
    • 14
    • 9
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 157
    • 109
    • 96
    • 34
    • 33
    • 24
    • 22
    • 20
    • 15
    • 10
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 犬, Pig
    宿主
    • 149
    • 18
    • 3
    • 2
    克隆类型
    • 153
    • 20
    多克隆
    标记
    • 86
    • 14
    • 11
    • 7
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    This PPARG antibody is un-conjugated
    应用范围
    • 155
    • 60
    • 55
    • 52
    • 52
    • 31
    • 22
    • 16
    • 14
    • 13
    • 7
    • 5
    • 5
    • 4
    • 2
    • 1
    Western Blotting (WB)
    序列
    MGETLGDSPI DPESDSFTDT LSANISQEMT MVDTEMPFWP TNFGISSVDL
    预测反应
    Dog: 92%, Human: 100%, Pig: 85%
    产品特性
    This is a rabbit polyclonal antibody against PPARG. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human PPARG
    Top Product
    Discover our top product PPARG Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 505 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    PPARG (Peroxisome Proliferator-Activated Receptor gamma (PPARG))
    别名
    PPARG (PPARG 产品)
    别名
    PPAR gamma antibody, PPARg2 antibody, PPARG antibody, Nr1c3 antibody, PPAR-gamma antibody, PPAR-gamma2 antibody, PPARgamma antibody, PPARgamma2 antibody, NR1C3 antibody, CIMT1 antibody, GLM1 antibody, PPARG1 antibody, PPARG2 antibody, xPPAR-gamma antibody, PPAR-GAMMA antibody, PPARGAMMA antibody, peroxisome proliferator-activated receptor gamma antibody, peroxisome proliferator activated receptor gamma antibody, peroxisome proliferator activated receptor gamma L homeolog antibody, PPARG antibody, Pparg antibody, pparg.L antibody
    背景
    PPARG is a receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcription. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. PPARG is the key regulator of adipocyte differentiation and glucose homeostasis.This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described.
    Alias Symbols: NR1C3, PPARG1, PPARG2, GLM1, CIMT1, PPARgamma
    Protein Interaction Partner: HDAC3, NCOA1, NCOA3, SUMO1, UBC, SUMO2, RXRA, MED1, HMGA1, EP300, NCOA2, CDC34, PRKAA2, PRKAA1, PPARGC1A, ASH2L, RBBP5, NSD1, NCOA6, PAXIP1, MUC1, NR3C1, SMAD2, CREBBP, ALOX15B, ZFYVE9, USP7, NCOR1, CDK5, SMARCD3, SMARCA4, NEDD4, BCAS2, MIF4GD, MED14, JAZ
    Protein Size: 505
    分子量
    57 kDa
    基因ID
    5468
    NCBI登录号
    NM_015869, NP_056953
    UniProt
    P37231
    途径
    MAPK Pathway, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Endopeptidase Activity, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
You are here:
客服