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Glucocorticoid Receptor 抗体 (N-Term)

NR3C1 适用: 人, 小鼠, 大鼠, Cow, 绵羊, Pig, 兔, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN784709
发货至: 中国
  • 抗原 See all Glucocorticoid Receptor (NR3C1) 抗体
    Glucocorticoid Receptor (NR3C1) (Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1))
    抗原表位
    • 21
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    N-Term
    适用
    • 162
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    人, 小鼠, 大鼠, Cow, 绵羊, Pig, 兔, 马
    宿主
    • 157
    • 15
    • 2
    克隆类型
    • 147
    • 27
    多克隆
    标记
    • 77
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    This Glucocorticoid Receptor antibody is un-conjugated
    应用范围
    • 158
    • 74
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    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    MDSKESLTPG REENPSSVLA QERGDVMDFY KTLRGGATVK VSASSPSLAV
    预测反应
    Cow: 79%, Horse: 79%, Human: 100%, Mouse: 79%, Pig: 79%, Rabbit: 86%, Rat: 86%, Sheep: 79%
    产品特性
    This is a rabbit polyclonal antibody against NR3C1. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human NR3C1
    Top Product
    Discover our top product NR3C1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 777 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    Glucocorticoid Receptor (NR3C1) (Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1))
    别名
    NR3C1 (NR3C1 产品)
    别名
    GR antibody, gcr antibody, grl antibody, xGR antibody, gccr antibody, gr antibody, zgc:113038 antibody, NR3C1 antibody, GCL antibody, LOC100302444 antibody, Gcr antibody, Grl antibody, Grl-1 antibody, Grl1 antibody, GRL antibody, GCCR antibody, GCR antibody, NO antibody, GR-A antibody, nr3c1 antibody, nuclear receptor subfamily 3 group C member 1 antibody, nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) antibody, nuclear receptor subfamily 3, group C, member 1 antibody, glucocorticoid receptor antibody, NR3C1 antibody, nr3c1 antibody, LOC100302444 antibody, Nr3c1 antibody
    背景
    NR3C1 is a receptor for glucocorticoids that can act as both a transcription factor and as a regulator of other transcription factors. This protein can also be found in heteromeric cytoplasmic complexes along with heat shock factors and immunophilins. The protein is typically found in the cytoplasm until it binds a ligand, which induces transport into the nucleus. Mutations in this gene are a cause of glucocorticoid resistance, or cortisol, resistance.
    Alias Symbols: GCCR, GCR, GR, GRL
    Protein Interaction Partner: TTC5, HSP90AA1, TXN2, UBC, TXN, FKBP5, DCAF6, RABEP2, BRCC3, LARP7, GAPVD1, CD2AP, SF3A1, HNRNPR, TRIM28, HDAC1, MTA2, CCDC6, CENPB, TMF1, PPARG, STUB1, BAG1, RPS6KA5, NCOA1, POLR1D, NCOA2, SRA1, PRKDC, RAD54L2, MAGEA11, PPP5C, PPID, GNB2, GNB1, FKBP4, GN
    Protein Size: 777
    分子量
    86 kDa
    基因ID
    2908
    NCBI登录号
    NM_001018076, NP_001018086
    UniProt
    P04150
    途径
    Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Muscle Cell Differentiation, Regulation of Carbohydrate Metabolic Process
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