Glucocorticoid Receptor 抗体 (N-Term)
(2 references)-
- 抗原 See all Glucocorticoid Receptor (NR3C1) 抗体
- Glucocorticoid Receptor (NR3C1) (Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1))
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抗原表位
- N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Glucocorticoid Receptor antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunocytochemistry (ICC)
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
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Rabbit Polyclonal antibody to Glucocorticoid receptor (nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor))
Glucocorticoid receptor antibody - 纯化方法
- Purified by antigen-affinity chromatography.
- 质量等级
- KO Validated
- 免疫原
- Recombinant protein encompassing a sequence within the N-terminus region of human Glucocorticoid Receptor. The exact sequence is proprietary.
- 亚型
- IgG
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anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) (AA 1-280) antibody
NR3C1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) antibodyNR3C1 适用: 人 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 6-00E-06 unconjugated
anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) (AA 51-140) antibodyNR3C1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2C8 unconjugated
anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) (AA 231-320) antibodyNR3C1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) (AA 1-373) antibodyNR3C1 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) (AA 598-755) antibodyNR3C1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) (Ser211) antibodyNR3C1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) (AA 1-190) antibodyNR3C1 适用: 人 WB, IHC, ELISA, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) (AA 532-730) antibodyNR3C1 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) (AA 41-184) antibodyNR3C1 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. IP: 1:500-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: A431 , mouse heart , rat heart , HeLa
Validation: KO/KD
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "Systems level-based RNAi screening by high content analysis identifies UBR5 as a regulator of estrogen receptor-α protein levels and activity." in: Oncogene, Vol. 34, Issue 2, pp. 154-64, (2015) (PubMed).
: "Coactivators enable glucocorticoid receptor recruitment to fine-tune estrogen receptor transcriptional responses." in: Nucleic acids research, Vol. 41, Issue 7, pp. 4036-48, (2013) (PubMed).
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: "Systems level-based RNAi screening by high content analysis identifies UBR5 as a regulator of estrogen receptor-α protein levels and activity." in: Oncogene, Vol. 34, Issue 2, pp. 154-64, (2015) (PubMed).
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- 抗原
- Glucocorticoid Receptor (NR3C1) (Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1))
- 别名
- nuclear receptor subfamily 3 group C member 1 (NR3C1 产品)
- 别名
- GR antibody, gcr antibody, grl antibody, xGR antibody, gccr antibody, gr antibody, zgc:113038 antibody, NR3C1 antibody, GCL antibody, LOC100302444 antibody, Gcr antibody, Grl antibody, Grl-1 antibody, Grl1 antibody, GRL antibody, GCCR antibody, GCR antibody, NO antibody, GR-A antibody, nr3c1 antibody, nuclear receptor subfamily 3 group C member 1 antibody, nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) antibody, nuclear receptor subfamily 3, group C, member 1 antibody, glucocorticoid receptor antibody, NR3C1 antibody, nr3c1 antibody, LOC100302444 antibody, Nr3c1 antibody
- 背景
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The protein encoded by this gene is a receptor for glucocorticoids that can act as both a transcription factor and as a regulator of other transcription factors. This protein can also be found in heteromeric cytoplasmic complexes along with heat shock factors and immunophilins. The protein is typically found in the cytoplasm until it binds a ligand, which induces transport into the nucleus. Mutations in this gene are a cause of glucocorticoid resistance, or cortisol, resistance. Alternate splicing, the use of at least three different promoters, and alternate translation initiation sites result in several transcript variants encoding the same protein or different isoforms, but the full-length nature of some variants has not been determined.
Cellular Localization: Cytoplasm , Nucleus - 分子量
- 86 kDa
- 基因ID
- 2908
- UniProt
- P04150
- 途径
- Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Muscle Cell Differentiation, Regulation of Carbohydrate Metabolic Process
