Glucocorticoid Receptor 抗体 (AA 231-320)
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北京 101111
Quick Overview for Glucocorticoid Receptor 抗体 (AA 231-320) (ABIN726875)
抗原
See all Glucocorticoid Receptor (NR3C1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 231-320
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Glucocorticoid receptor
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亚型
- IgG
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anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) (AA 51-140) antibody
NR3C1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2C8 unconjugated
anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) (N-Term) antibodyKO Validated NR3C1 适用: 人 WB, IP, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) antibodyNR3C1 适用: 人 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 6E6 unconjugated
anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) (AA 1-373) antibodyNR3C1 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) (AA 598-755) antibodyNR3C1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) (Ser211) antibodyNR3C1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) (AA 1-190) antibodyNR3C1 适用: 人 WB, IHC, ELISA, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) (AA 1-373) antibodyNR3C1 适用: 人 WB, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) (pSer211) antibodyNR3C1 适用: 人, 小鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) (Ser226), (Ser234), (Ser246) antibodyNR3C1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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: "Androgen receptor reverts dexamethasone‑induced inhibition of prostate cancer cell proliferation and migration." in: Molecular medicine reports, Vol. 17, Issue 4, pp. 5887-5893, (2018) (PubMed).
: "Expression of glucocorticoid receptor-α in the epidermis of patients with psoriasis vulgaris." in: Experimental and therapeutic medicine, Vol. 10, Issue 2, pp. 419-422, (2015) (PubMed).
: "Glucocorticoid receptor-dependent immunomodulatory effect of ursodeoxycholic acid on liver lymphocytes in mice." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 305, Issue 6, pp. G427-38, (2013) (PubMed).
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: "Androgen receptor reverts dexamethasone‑induced inhibition of prostate cancer cell proliferation and migration." in: Molecular medicine reports, Vol. 17, Issue 4, pp. 5887-5893, (2018) (PubMed).
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- Glucocorticoid Receptor (NR3C1) (Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1))
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别名
- Glucocorticoid receptor
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背景
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Synonyms: GR, GCR, GRL, GCCR, GCRST, Glucocorticoid receptor, Nuclear receptor subfamily 3 group C member 1, NR3C1
Background: Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth. Involved in chromatin remodeling. May play a negative role in adipogenesis through the regulation of lipolytic and antilipogenic genes expression.
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基因ID
- 2908
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UniProt
- P04150
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途径
- Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Muscle Cell Differentiation, Regulation of Carbohydrate Metabolic Process
抗原
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