MAP2K3 抗体 (N-Term)
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北京 101111
Quick Overview for MAP2K3 抗体 (N-Term) (ABIN2777128)
抗原
See all MAP2K3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- MAP2K3 Antibody - N-terminal region
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序列
- SKPPAPNPTP PRNLDSRTFI TIGDRNFEVE ADDLVTISEL GRGAYGVVEK
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预测反应
- Cow: 86%, Dog: 93%, Goat: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%
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产品特性
- This is a rabbit polyclonal antibody against MAP2K3. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human MAP2K3
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anti-Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) (AA 1-170) antibody
MAP2K3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) (AA 1-138) antibodyMAP2K3 适用: 人 IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 2E12D11 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) antibodyKD Validated MAP2K3 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 23GB2420 unconjugated Recombinant Antibody
anti-Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) antibodyMAP2K3 适用: 人, 小鼠, 犬, 猴 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 5D3 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) antibodyMAP2K3 适用: 人, 犬, 猴 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 5C7 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) (C-Term) antibodyMAP2K3 适用: 人, 小鼠, 大鼠 WB, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) antibodyMAP2K3 适用: 人, 小鼠, 大鼠, 犬, 猴 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 5F2 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) (AA 1-100) antibodyMAP2K3 适用: 人 WB, ELISA, IHC (p), IP 宿主: 小鼠 Monoclonal 1D10 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) (AA 15-45), (N-Term) antibodyMAP2K3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB0928 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) antibodyMAP2K3 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP42064-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- MAP2K3 (Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3))
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别名
- MAP2K3
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背景
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Background Information: MAP2K3 is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells. The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis. The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells. The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis. Multiple alternatively spliced transcript variants that encode distinct isoforms have been reported for this gene.
Gene Name: Mitogen-activated protein kinase kinase 3
Alternative Symbols: MEK3, MKK3, MAPKK3, PRKMK3, SAPKK2, SAPKK-2
Protein Name: Dual specificity mitogen-activated protein kinase kinase 3
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分子量
- 36kDa
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基因ID
- 5606
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NCBI登录号
- NP_002747
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UniProt
- P46734
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途径
- MAPK Pathway, TLR signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Autophagy, Signaling Events mediated by VEGFR1 and VEGFR2
抗原
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