MCM2 抗体 (N-Term)
(1 reference)Quick Overview for MCM2 抗体 (N-Term) (ABIN2774882)
抗原
See all MCM2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- PGRSSRRTDA LTSSPGRDLP PFEDESEGLL GTEGPLEEEE DGEELIGDGM
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预测反应
- Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against MCM2. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human MCM2
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anti-Minichromosome Maintenance Complex Component 2 (MCM2) antibody
MCM2 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 2B3 unconjugated
anti-Minichromosome Maintenance Complex Component 2 (MCM2) antibodyMCM2 适用: 人 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 1E7 unconjugated
anti-Minichromosome Maintenance Complex Component 2 (MCM2) (AA 805-904) antibodyMCM2 适用: 人 WB, ELISA, IF, IP 宿主: 小鼠 Monoclonal 6A8 unconjugated
anti-Minichromosome Maintenance Complex Component 2 (MCM2) antibodyMCM2 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Minichromosome Maintenance Complex Component 2 (MCM2) (AA 884-904) antibodyMCM2 适用: 小鼠, 大鼠 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 2 (MCM2) (N-Term) antibodyMCM2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 2 (MCM2) (AA 360-700) antibodyMCM2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 2 (MCM2) (AA 889-904), (C-Term) antibodyMCM2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 2 (MCM2) (AA 884-904), (C-Term) antibodyMCM2 适用: 小鼠, 大鼠 WB, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 2 (MCM2) (AA 649-677) antibodyMCM2 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 904 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Prohibitin physically interacts with MCM proteins and inhibits mammalian DNA replication." in: Cell cycle (Georgetown, Tex.), Vol. 8, Issue 10, pp. 1621-9, (2009) (PubMed).
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: "Prohibitin physically interacts with MCM proteins and inhibits mammalian DNA replication." in: Cell cycle (Georgetown, Tex.), Vol. 8, Issue 10, pp. 1621-9, (2009) (PubMed).
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- MCM2 (Minichromosome Maintenance Complex Component 2 (MCM2))
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别名
- MCM2
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背景
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The protein encoded by MCM2 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7.
Alias Symbols: BM28, CCNL1, CDCL1, cdc19, D3S3194, MITOTIN
Protein Interaction Partner: HUWE1, MCM6, CHFR, SUMO2, MCMBP, UBC, SUMO1, MDM2, MCM7, MCM4, HSP90AB1, ACLY, PRRC1, HYOU1, CAP1, NCL, POLA1, TONSL, SNF8, ELL, TCEA1, POLR2A, CDK6, CDK4, CDC6, MCM10, ORC6, CCNB2, VCAM1, P2RX4, ORC5, ORC2, MCM5, MCM3, ITGA4, FN1, CSNK2A1, CDKN2A, DBF4,
Protein Size: 904 -
分子量
- 99 kDa
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基因ID
- 4171
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NCBI登录号
- NM_004526, NP_004517
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UniProt
- P49736
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途径
- DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
抗原
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