CDKN2B 抗体 (Middle Region)
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- 抗原 See all CDKN2B 抗体
- CDKN2B (Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B))
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抗原表位
- Middle Region
- 适用
- 人, 小鼠, 大鼠, Pig, 犬, 兔, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CDKN2B antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- REGFLDTLVV LHRAGARLDV RDAWGRLPVD LAEERGHRDV AGYLRTATGD
- 预测反应
- Dog: 91%, Guinea Pig: 83%, Mouse: 83%, Pig: 100%, Rabbit: 91%, Rat: 83%
- 产品特性
- This is a rabbit polyclonal antibody against CDKN2B. It was validated on Western Blot using a cell lysate as a positive control.
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human CDKN2B
- Top Product
- Discover our top product CDKN2B Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 138 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- CDKN2B (Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B))
- 别名
- CDKN2B (CDKN2B 产品)
- 别名
- p14-INK4b antibody, cdk4l antibody, ink4b antibody, mts2 antibody, p15 antibody, p15ink4b antibody, tp15 antibody, CDK4I antibody, INK4B antibody, MTS2 antibody, P15 antibody, TP15 antibody, p15INK4b antibody, AV083695 antibody, INK4b antibody, p15(INK4b) antibody, CDKN2A antibody, cyclin dependent kinase inhibitor 2B antibody, Cyclin-dependent kinase 4 inhibitor B antibody, cyclin-dependent kinase inhibitor 2B antibody, cyclin-dependent kinase inhibitor 2B L homeolog antibody, cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) antibody, CDKN2B antibody, cdn2b antibody, cdkn2b antibody, cdkn2b.L antibody, Cdkn2b antibody
- 背景
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CDKN2B's gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. CDKN2B is a cyclin-dependent kinase inhibitor, which forms a complex with CDK4 or CDK6, and prevents the activation of the CDK kinases, thus the encoded protein functions as a cell growth regulator that controls cell cycle G1 progression. The expression of this gene was found to be dramatically induced by TGF beta, which suggested its role in the TGF beta induced growth inhibition.
Alias Symbols: P15, MTS2, TP15, CDK4I, INK4B, p15INK4b
Protein Interaction Partner: UBC, TRAF1, CDK6, CCDC33, NIF3L1, CDK4, PYCRL, RNF20, TGFB1I1, ISL1, APP, KIAA1377, CCDC90B, ARPC3, ZBTB17, IKBKAP, CDK8, MAGEA11, PIAS2,
Protein Size: 138 - 分子量
- 15 kDa
- 基因ID
- 1030
- NCBI登录号
- NM_004936, NP_004927
- UniProt
- P42772
- 途径
- Cell Division Cycle, Mitotic G1-G1/S Phases
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