NR1H4 抗体 (Middle Region)
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- 抗原 See all NR1H4 抗体
- NR1H4 (Nuclear Receptor Subfamily 1, Group H, Member 4 (NR1H4))
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抗原表位
- Middle Region
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适用
- 人, 大鼠, 小鼠, 犬, 马, Cow, 兔, Pig, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NR1H4 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- SAVEAMFLRS AEIFNKKLPS GHSDLLEERI RNSGISDEYI TPMFSFYKSI
- 预测反应
- Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 93%
- 产品特性
- This is a rabbit polyclonal antibody against NR1H4. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human NR1H4
- Top Product
- Discover our top product NR1H4 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 472 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Guggulsterone suppresses bile acid-induced and constitutive caudal-related homeobox 2 expression in gut-derived adenocarcinoma cells." in: Anticancer research, Vol. 30, Issue 6, pp. 1953-60, (2010) (PubMed).
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Guggulsterone suppresses bile acid-induced and constitutive caudal-related homeobox 2 expression in gut-derived adenocarcinoma cells." in: Anticancer research, Vol. 30, Issue 6, pp. 1953-60, (2010) (PubMed).
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- 抗原
- NR1H4 (Nuclear Receptor Subfamily 1, Group H, Member 4 (NR1H4))
- 别名
- NR1H4 (NR1H4 产品)
- 别名
- zgc:110190 antibody, zgc:92742 antibody, NR1H4 antibody, BAR antibody, FXR antibody, HRR-1 antibody, HRR1 antibody, RIP14 antibody, AI957360 antibody, Fxr antibody, Rxrip14 antibody, nuclear receptor subfamily 1, group H, member 5 S homeolog antibody, nuclear receptor subfamily 1, group H, member 4 antibody, nuclear receptor subfamily 1 group H member 4 antibody, nr1h5.S antibody, nr1h4 antibody, NR1H4 antibody, Nr1h4 antibody
- 背景
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NR1H4 is the receptor for bile acids such as chenodeoxycholic acid, lithocholic acid and deoxycholic acid. NR1H4 represses the transcription of the cholesterol 7-alpha-hydroxylase gene (CYP7A1) through the induction of NR0B2 or FGF19 expression, via two d
Alias Symbols: BAR, FXR, HRR-1, HRR1, MGC163445, RIP14
Protein Interaction Partner: SMARCD3, HDAC6, SUMO1, NCOR2, ESR1, RRM2, GPS2, RXRG, GAPDH, RXRA, EP300, SIRT1, SRC, NCOA6, CARM1, HIST1H4A, HIST1H3A, PRMT1, NCOR1, XRCC5, PRKDC, XRCC6, NCOA1, CASP8, SMARCD1,
Protein Size: 472 - 分子量
- 54 kDa
- 基因ID
- 9971
- NCBI登录号
- NM_005123, NP_005114
- UniProt
- B6ZGS9
- 途径
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Carbohydrate Metabolic Process
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