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NR1H4 抗体 (Middle Region)

NR1H4 适用: 人, 大鼠, 小鼠, 犬, 马, Cow, 兔, Pig, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2773865
发货至: 中国
  • 抗原 See all NR1H4 抗体
    NR1H4 (Nuclear Receptor Subfamily 1, Group H, Member 4 (NR1H4))
    抗原表位
    • 16
    • 12
    • 9
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 55
    • 27
    • 26
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    人, 大鼠, 小鼠, 犬, 马, Cow, 兔, Pig, 豚鼠
    宿主
    • 52
    • 5
    • 1
    克隆类型
    • 53
    • 5
    多克隆
    标记
    • 28
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NR1H4 antibody is un-conjugated
    应用范围
    • 50
    • 27
    • 13
    • 13
    • 12
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB)
    序列
    SAVEAMFLRS AEIFNKKLPS GHSDLLEERI RNSGISDEYI TPMFSFYKSI
    预测反应
    Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 93%
    产品特性
    This is a rabbit polyclonal antibody against NR1H4. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human NR1H4
    Top Product
    Discover our top product NR1H4 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 472 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Yamada, Osawa, Hamaya, Furuta, Hishida, Kajimura, Ikuma: "Guggulsterone suppresses bile acid-induced and constitutive caudal-related homeobox 2 expression in gut-derived adenocarcinoma cells." in: Anticancer research, Vol. 30, Issue 6, pp. 1953-60, (2010) (PubMed).

  • 抗原
    NR1H4 (Nuclear Receptor Subfamily 1, Group H, Member 4 (NR1H4))
    别名
    NR1H4 (NR1H4 产品)
    别名
    zgc:110190 antibody, zgc:92742 antibody, NR1H4 antibody, BAR antibody, FXR antibody, HRR-1 antibody, HRR1 antibody, RIP14 antibody, AI957360 antibody, Fxr antibody, Rxrip14 antibody, nuclear receptor subfamily 1, group H, member 5 S homeolog antibody, nuclear receptor subfamily 1, group H, member 4 antibody, nuclear receptor subfamily 1 group H member 4 antibody, nr1h5.S antibody, nr1h4 antibody, NR1H4 antibody, Nr1h4 antibody
    背景
    NR1H4 is the receptor for bile acids such as chenodeoxycholic acid, lithocholic acid and deoxycholic acid. NR1H4 represses the transcription of the cholesterol 7-alpha-hydroxylase gene (CYP7A1) through the induction of NR0B2 or FGF19 expression, via two d
    Alias Symbols: BAR, FXR, HRR-1, HRR1, MGC163445, RIP14
    Protein Interaction Partner: SMARCD3, HDAC6, SUMO1, NCOR2, ESR1, RRM2, GPS2, RXRG, GAPDH, RXRA, EP300, SIRT1, SRC, NCOA6, CARM1, HIST1H4A, HIST1H3A, PRMT1, NCOR1, XRCC5, PRKDC, XRCC6, NCOA1, CASP8, SMARCD1,
    Protein Size: 472
    分子量
    54 kDa
    基因ID
    9971
    NCBI登录号
    NM_005123, NP_005114
    UniProt
    B6ZGS9
    途径
    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Carbohydrate Metabolic Process
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