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SET/TAF-I 抗体

SET 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2764139
发货至: 中国
  • 抗原 See all SET/TAF-I (SET) 抗体
    SET/TAF-I (SET) (SET Nuclear Oncogene (SET))
    适用
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    宿主
    • 67
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    克隆类型
    • 58
    • 13
    多克隆
    标记
    • 35
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    This SET/TAF-I antibody is un-conjugated
    应用范围
    • 53
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    Western Blotting (WB)
    交叉反应
    产品特性
    SET, SET translocation (myeloid leukemia-associated), Protein SET, Phosphatase 2A inhibitor, I2PP2A, I-2PP2A, Template-activating factor I, TAF-I, HLA-DR-associated protein II, PHAPII, Inhibitor of granzyme A-activated DNase, IGAAD2PP2A, IGAAD, I2PP2A,Human SET was originally identified as part of the SET-CAN fusion gene produced by a somatic translocation event in a patient with acute undifferentiated leukemia. In developing kidney, SET is highly expressed in the zone of nephron morphogenesis. SET has been shown to be a potent and specific inhibitor of protein phosphatase 2A, a family of major serine/threonine phosphatases involved in regulating cell proliferation and differentiation. SET is also involved in the regulation of renal cell proliferation and tumorigenesis. SET mRNA expression is markedly reduced in cells rendered quiescent by serum starvation, contact inhibition, or differentiation. SET protein expression is also much greater in developing rat and human kidney than in fully differentiated, mature kidney. High levels of SET mRNA and SET protein expression arefound in Wilms' tumor, but not in renal cell carcinoma, adult polycystic kidney disease or in transitional cell carcinoma.
    纯化方法
    Antigen Immunoaffiinity Purification
    免疫原
    Synthetic peptide derived from the human SET protein
    亚型
    IgG
    Top Product
    Discover our top product SET Primary Antibody
  • 应用备注
    Antibody can be used for Western blotting (1:400 dilution). Optimal concentration should be evaluated by serial dilutions.
    限制
    仅限研究用
  • 浓度
    Lot specific
    缓冲液
    Provided as solution in phosphate buffered saline with 0.08 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -80 °C
    储存方法
    Product should be stored at -70°C. Aliquot to avoid freeze/thaw cycles
  • 抗原
    SET/TAF-I (SET) (SET Nuclear Oncogene (SET))
    别名
    SET (SET 产品)
    别名
    2PP2A antibody, I2PP2A antibody, IGAAD antibody, IPP2A2 antibody, PHAPII antibody, TAF-I antibody, TAF-IBETA antibody, 2610030F17Rik antibody, 5730420M11Rik antibody, AA407739 antibody, I-2PP2A antibody, StF-IT-1 antibody, 2pp2a antibody, i2pp2a antibody, igaad antibody, ipp2a2 antibody, phapii antibody, set antibody, set-a antibody, set-b antibody, taf-ibeta antibody, wu:fb30g11 antibody, wu:fd16c08 antibody, SET nuclear proto-oncogene antibody, SET nuclear oncogene antibody, SET translocation antibody, SET nuclear proto-oncogene L homeolog antibody, SET nuclear proto-oncogene b antibody, SET antibody, Set antibody, LOC403555 antibody, set.L antibody, setb antibody
    UniProt
    Q01105
    途径
    Apoptosis
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