MTA1 抗体
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- 抗原 See all MTA1 抗体
- MTA1 (Metastasis Associated 1 (MTA1))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MTA1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of MTA1 protein. (region surrounding Lys182)
- 交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
- 纯度
- > 95 % pure by SDS-PAGE
- Top Product
- Discover our top product MTA1 Primary Antibody
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anti-Metastasis Associated 1 (MTA1) (AA 601-700) antibody
MTA1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4D11 unconjugated
anti-Metastasis Associated 1 (MTA1) (AA 601-700) antibodyMTA1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 4D5 unconjugated
anti-Metastasis Associated 1 (MTA1) (AA 601-700) antibodyMTA1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1C3 unconjugated
anti-Metastasis Associated 1 (MTA1) (AA 541-715) antibodyMTA1 适用: 人 WB, ELISA, IHC, ICC, FACS, Neut 宿主: 小鼠 Monoclonal 6B1E9 unconjugated
anti-Metastasis Associated 1 (MTA1) (AA 601-715) antibodyMTA1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Metastasis Associated 1 (MTA1) antibodyMTA1 适用: 人 IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Metastasis Associated 1 (MTA1) (AA 541-715) antibodyMTA1 适用: 人 WB, ELISA, IHC, ICC, FACS, Neut 宿主: 小鼠 Monoclonal 7G9C10 unconjugated
anti-Metastasis Associated 1 (MTA1) (Internal Region) antibodyMTA1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Metastasis Associated 1 (MTA1) (Internal Region) antibodyVerified MTA1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Metastasis Associated 1 (MTA1) (AA 659-687), (C-Term) antibodyMTA1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal RB40949 unconjugated
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- 应用备注
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ELISA: 1: 5000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1,0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- DO NOT FREEZE!
- 储存条件
- 4 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C.
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- 抗原
- MTA1 (Metastasis Associated 1 (MTA1))
- 别名
- MTA1 (MTA1 产品)
- 别名
- Tex22 antibody, metastasis associated 1 antibody, metastasis associated 1 L homeolog antibody, MTA1 antibody, Mta1 antibody, mta1.L antibody
- 背景
- MTA1 (metastasis-associated protein 1) is a component of the NURD (for nucleosome remodeling and histone deacetylation) complex, which is associated with ATP-dependent chromatin-remodeling and histone deacetylase activity. MTA1 functions in conjunction with other components of NURD to mediate transcriptional repression as it facilitates the association of repressor molecules with the chromatin. Structurally, MTA1 contains a single SH3-binding motif and a zinc finger domain, along with a region similar to the corepressor protein N-Cor. MTA1 is normally expressed at low levels in various tissues and is more highly expressed in testis. Overexpression of MTA1 correlates with tumor invasion and metastasis in various carcinomas including colorectal, gastrointestinal and breast carcinomas. Elevated MTA1 levels in these tumors appears to enhance the metastases to lymph nodes, increase mammary cell motility and potentiate growth, and it may, therefore, be an indicator for assessing the potential malignancies of various tumors. A similar protein, MTA1-L1 (MTA1-like protein 1), shares more than 55 % sequence homology with MTA1 and is ubiquitously expressed.Synonyms: Metastasis-associated protein MTA1
- 分子量
- approx. 80 kDa
- 基因ID
- 9112
- NCBI登录号
- NP_001190187
- UniProt
- Q13330
- 途径
- Chromatin Binding
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