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MTA1 抗体 (C-Term)

MTA1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal RB40949 unconjugated
产品编号 ABIN1881556
发货至: 中国
  • 抗原 See all MTA1 抗体
    MTA1 (Metastasis Associated 1 (MTA1))
    抗原表位
    • 13
    • 10
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 659-687, C-Term
    适用
    • 54
    • 25
    • 21
    • 7
    • 7
    • 7
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 47
    • 7
    • 1
    克隆类型
    • 48
    • 7
    多克隆
    标记
    • 38
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MTA1 antibody is un-conjugated
    应用范围
    • 44
    • 27
    • 14
    • 11
    • 9
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    预测反应
    Rat
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This MTA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 659-687 amino acids from the C-terminal region of human MTA1.
    克隆位点
    RB40949
    亚型
    Ig Fraction
    Top Product
    Discover our top product MTA1 Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Zhu, Guo, Li, Ding, Chen: "Metastasis-associated protein 1 nuclear expression is associated with tumor progression and clinical outcome in patients with non-small cell lung cancer." in: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, Vol. 5, Issue 8, pp. 1159-66, (2010) (PubMed).

    Van Rechem, Boulay, Pinte, Stankovic-Valentin, Guérardel, Leprince: "Differential regulation of HIC1 target genes by CtBP and NuRD, via an acetylation/SUMOylation switch, in quiescent versus proliferating cells." in: Molecular and cellular biology, Vol. 30, Issue 16, pp. 4045-59, (2010) (PubMed).

    Yang, Liu, Li: "[Expression of Mta-1 and VEGF and their correlation in the endometrial cancer]." in: Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, Vol. 26, Issue 7, pp. 682-4, (2010) (PubMed).

    Li, Ohshiro, Khan, Kumar: "Requirement of MTA1 in ATR-mediated DNA damage checkpoint function." in: The Journal of biological chemistry, Vol. 285, Issue 26, pp. 19802-12, (2010) (PubMed).

    Li, Pakala, Reddy, Ohshiro, Peng, Lian, Fu, Kumar: "Revelation of p53-independent function of MTA1 in DNA damage response via modulation of the p21 WAF1-proliferating cell nuclear antigen pathway." in: The Journal of biological chemistry, Vol. 285, Issue 13, pp. 10044-52, (2010) (PubMed).

  • 抗原
    MTA1 (Metastasis Associated 1 (MTA1))
    别名
    MTA1 (MTA1 产品)
    别名
    Tex22 antibody, metastasis associated 1 antibody, metastasis associated 1 L homeolog antibody, MTA1 antibody, Mta1 antibody, mta1.L antibody
    背景
    This gene encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues. The role it plays in metastasis is unclear. It was initially thought to be the 70kD component of a nucleosome remodeling deacetylase complex, NuRD, but it is more likely that this component is a different but very similar protein. These two proteins are so closely related, though, that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. The profile and activity of this gene product suggest that it is involved in regulating transcription and that this may be accomplished by chromatin remodeling. [provided by RefSeq].
    分子量
    80786
    NCBI登录号
    NP_001190187, NP_004680
    UniProt
    Q13330
    途径
    Chromatin Binding
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