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MTA1 抗体

MTA1 适用: 人 IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2854809
发货至: 中国
  • 抗原 See all MTA1 抗体
    MTA1 (Metastasis Associated 1 (MTA1))
    适用
    • 54
    • 26
    • 22
    • 7
    • 7
    • 7
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 47
    • 7
    • 1
    克隆类型
    • 48
    • 7
    多克隆
    标记
    • 38
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MTA1 antibody is un-conjugated
    应用范围
    • 45
    • 27
    • 14
    • 10
    • 8
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC)
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Rabbit Polyclonal antibody to MTA1 (metastasis associated 1)
    MTA1 antibody [C1C3]
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human MTA1. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product MTA1 Primary Antibody
  • 应用备注
    ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    MTA1 (Metastasis Associated 1 (MTA1))
    别名
    metastasis associated 1 (MTA1 产品)
    别名
    Tex22 antibody, metastasis associated 1 antibody, metastasis associated 1 L homeolog antibody, MTA1 antibody, Mta1 antibody, mta1.L antibody
    背景
    This gene encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues. The role it plays in metastasis is unclear. It was initially thought to be the 70kD component of a nucleosome remodeling deacetylase complex, NuRD, but it is more likely that this component is a different but very similar protein. These two proteins are so closely related, though, that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. The profile and activity of this gene product suggest that it is involved in regulating transcription and that this may be accomplished by chromatin remodeling.

    Cellular Localization: Isoform Short: Cytoplasm , Isoform Long: Nucleus
    分子量
    81 kDa
    基因ID
    9112
    UniProt
    Q13330
    途径
    Chromatin Binding
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