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NFATC3 抗体

NFATC3 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN272044
发货至: 中国
  • 抗原 See all NFATC3 抗体
    NFATC3 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 3 (NFATC3))
    适用
    • 46
    • 40
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 53
    • 7
    • 1
    • 1
    克隆类型
    • 58
    • 4
    多克隆
    标记
    • 36
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NFATC3 antibody is un-conjugated
    应用范围
    • 44
    • 23
    • 14
    • 13
    • 13
    • 12
    • 8
    • 6
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects endogenous levels of NFAT4 protein. (region surrounding Glu159)
    交叉反应 (详细)
    Species reactivity (tested):Human and Mouse.
    纯化方法
    Affinity Chromatography using epitope-specific immunogen.
    Top Product
    Discover our top product NFATC3 Primary Antibody
  • 应用备注
    ELISA: 1/10000approx. 1/20000. Western Blot: 1/500approx. 1/1000. Immunohistochemistry: 1/50-1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.2., 0.05 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    NFATC3 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 3 (NFATC3))
    别名
    NFAT4 / NFATC3 (NFATC3 产品)
    别名
    NFATC3 antibody, NFATx antibody, nf-at antibody, nfat4 antibody, nfatx antibody, C80703 antibody, D8Ertd281e antibody, NFAT4 antibody, NFATX antibody, nuclear factor of activated T-cells 3 antibody, nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3 antibody, nuclear factor of activated T-cells 3 S homeolog antibody, NFATC3 antibody, nfatc3 antibody, Nfatc3 antibody, nfatc3.S antibody
    背景
    NFATc4 (nuclear factor of activated T cells, cytoplasmic, calcineurindependent 4) is a member of the nuclear factors of activated T cells DNAbinding transcription complex that influences cytokine gene expression, cardiac hypertrophy and adipocyte differentiation. This complex consists of at least two components, a cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family participate in the formation of this complex. NFATc4 plays a role in the inducible expression of cytokine genes in T cells, including the induction of IL-2 and IL-4. p38 MAP kinase phosphorylates multiple residues in the NFAT homology domain of NFATc4.Synonyms: NF-ATc3, NFATc3, Nuclear factor of activated T-cells, T-cell transcription factor NFAT4, T-cell transcription factor NFAT4, cytoplasmic 3
    分子量
    approx. 115 kDa
    基因ID
    4775
    NCBI登录号
    NP_004546
    UniProt
    Q12968
    途径
    RTK signaling, WNT signaling, Fc-epsilon Receptor Signaling Pathway, Chromatin Binding
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