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PRKAB1 抗体 (AA 2-100) (Alexa Fluor 647)

PRKAB1 适用: 人, 大鼠 WB, IF (cc), IF (p) 宿主: 兔 Polyclonal Alexa Fluor 647
产品编号 ABIN2690022
发货至: 中国
  • 抗原 See all PRKAB1 抗体
    PRKAB1 (Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1))
    抗原表位
    • 20
    • 17
    • 15
    • 15
    • 14
    • 10
    • 9
    • 8
    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2-100
    适用
    • 114
    • 98
    • 96
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 大鼠
    宿主
    • 136
    • 9
    克隆类型
    • 127
    • 18
    多克隆
    标记
    • 52
    • 9
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 1
    This PRKAB1 antibody is conjugated to Alexa Fluor 647
    应用范围
    • 80
    • 64
    • 64
    • 47
    • 29
    • 21
    • 15
    • 15
    • 11
    • 7
    • 5
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    人, 大鼠
    预测反应
    Chicken
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human AMPK beta 1
    亚型
    IgG
    Top Product
    Discover our top product PRKAB1 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    PRKAB1 (Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1))
    别名
    AMPK beta 1 (PRKAB1 产品)
    别名
    AMPK antibody, HAMPKb antibody, 1300015D22Rik antibody, AU021155 antibody, E430008F22 antibody, MGC82489 antibody, prkab1 antibody, wu:fk93d05 antibody, wu:fw87e09 antibody, zgc:56652 antibody, zgc:76975 antibody, zgc:92228 antibody, protein kinase AMP-activated non-catalytic subunit beta 1 antibody, protein kinase, AMP-activated, beta 1 non-catalytic subunit antibody, protein kinase, AMP-activated, beta 1 non-catalytic subunit S homeolog antibody, protein kinase, AMP-activated, beta 1 non-catalytic subunit, b antibody, protein kinase, AMP-activated, beta 1 non-catalytic subunit, a antibody, PRKAB1 antibody, Prkab1 antibody, prkab1.S antibody, prkab1 antibody, prkab1b antibody, prkab1a antibody
    背景

    Synonyms: AMPK, HAMPKb, 5'-AMP-activated protein kinase subunit beta-1, AMPK subunit beta-1, AMPKb, PRKAB1

    Background: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton, probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

    基因ID
    5564
    UniProt
    Q9Y478
    途径
    AMPK Signaling, Warburg Effect
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