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IL-6 抗体 (Biotin)

This 大鼠 单克隆 antibody specifically detects IL-6 in WB 和 ELISA. It exhibits reactivity toward 小鼠. It has been mentioned in 3+ publications
产品编号 ABIN2689781
发货至: 中国
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Quick Overview for IL-6 抗体 (Biotin) (ABIN2689781)

抗原

See all IL-6 (IL6) 抗体
IL-6 (IL6) (Interleukin 6 (IL6))

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This IL-6 antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), ELISA

克隆位点

MP5
  • 产品特性

    The MP5-32C11 antibody reacts with mouse interleukin-6 (IL-6). The immunogen used to generate the MP5-32C11 hybridoma was recombinant mouse IL-6. This is a non-neutralizing antibody.

    BD Pharmingen™ Biotin Rat Anti-Mouse IL-6 - Biotin - Clone MP5-32C11 - Isotype Rat IgG2a - Reactivity Ms - 0.5 mg

    纯化方法

    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

    免疫原

    Recombinant mouse IL-6

    亚型

    IgG2a
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Aqueous buffered solution containing ≤0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.

    储存条件

    4 °C

    储存方法

    Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
  • Abrams: "Immunoenzymetric assay of mouse and human cytokines using NIP-labeled anti-cytokine antibodies." in: Current protocols in immunology / edited by John E. Coligan ... [et al.], Vol. Chapter 6, pp. Unit 6.20, (2008) (PubMed).

    Abrams, Roncarolo, Yssel, Andersson, Gleich, Silver: "Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples." in: Immunological reviews, Vol. 127, Issue 9-10, pp. 5-24, (1992) (PubMed).

    Starnes, Pearce, Tewari, Yim, Zou, Abrams: "Anti-IL-6 monoclonal antibodies protect against lethal Escherichia coli infection and lethal tumor necrosis factor-alpha challenge in mice." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 145, Issue 12, pp. 4185-91, (1991) (PubMed).

  • 抗原

    IL-6 (IL6) (Interleukin 6 (IL6))

    别名

    IL-6

    途径

    TLR signaling, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome
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