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- 抗原 See all KLRK1 抗体
- KLRK1 (Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This KLRK1 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS)
- 品牌
- Ultra-LEAF™
- 纯化方法
- The Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
- 过滤
- 0.2 μm filtered
- 内毒素水平
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Endotoxin level is <0.01 EU/μg of the protein (<0.001 ng/μg of the protein) as determined by the LAL test.
- 克隆位点
- 1D11
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product KLRK1 Primary Antibody
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anti-Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) (AA 73-216) antibody
KLRK1 适用: 人 WB, FACS, ELISA 宿主: 小鼠 Monoclonal 5C9B4 unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) (AA 121-219) antibodyKLRK1 适用: 小鼠 WB, FACS, ELISA, IHC (fro), IF (cc), IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) antibody (FITC)KLRK1 适用: 人 FACS 宿主: 小鼠 Monoclonal 1D11 FITC
anti-Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) antibodyKLRK1 适用: 人 FACS, IP, IHC (fro), Func 宿主: 小鼠 Monoclonal 1D11 unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) antibodyKLRK1 适用: 人 FACS, IP, IHC (fro) 宿主: 小鼠 Monoclonal 1D11 unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) (AA 167-216) antibodyKLRK1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) (AA 73-216) antibodyKLRK1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) (AA 92-216) antibodyKLRK1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) (AA 90-232) antibodyKLRK1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) (AA 75-215) antibodyKLRK1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 储存液
- Azide free
- 注意事项
- This Ultra-LEAF™ solution contains no preservative, handle under aseptic conditions
- 储存条件
- 4 °C
- 储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- 抗原
- KLRK1 (Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1))
- 别名
- CD314 (KLRK1 产品)
- 别名
- KLRK1 antibody, NKG2D antibody, CD314 antibody, D12S2489E antibody, KLR antibody, NKG2-D antibody, D6H12S2489E antibody, Nkg2d antibody, Nkrp2 antibody, killer cell lectin like receptor K1 antibody, killer cell lectin-like receptor subfamily K, member 1 antibody, NKG2D protein antibody, KLRK1 antibody, Klrk1 antibody, NKG2D antibody
- 背景
- CD314 is a homodimeric C-type lectin-like protein also known as NKG2D. It is expressed on NK cells, CD8+ T cells, γ/ δ T cells, and in vitro induced LAK cells. Several molecules have been identified as the ligands for NKG2D, including MHC class-I chain-related protein A (MICA), MICB, and UL16-binding proteins (ULBPs). NKG2D has no intrinsic signaling capacity, but attains this by non-covalent association with DAP10 or DAP12 adaptors. In addition to being a primary activation receptor on NK cells, NKG2D is also a costimulatory receptor for TCR-mediated T cell proliferation and cytokine production. The interaction of NKG2D with its ligands plays a role in the immune surveillance against pathogen and tumor cells, and in the pathogenesis of autoimmune diseases.
- 途径
- Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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