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CD276 抗体

CD276 适用: 人 FACS 宿主: 小鼠 Monoclonal DCN-70 unconjugated
产品编号 ABIN2664485
发货至: 中国
  • 抗原 See all CD276 抗体
    CD276
    适用
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    宿主
    • 42
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    小鼠
    克隆类型
    • 38
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    单克隆
    标记
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    This CD276 antibody is un-conjugated
    应用范围
    • 49
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    Flow Cytometry (FACS)
    纯化方法
    The antibody was purified by affinity chromatography.
    克隆位点
    DCN-70
    亚型
    IgG1 kappa
    Top Product
    Discover our top product CD276 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    CD276
    别名
    CD276 (CD276 产品)
    别名
    sc:d0645 antibody, zgc:158279 antibody, 6030411F23Rik antibody, AU016588 antibody, B7RP-2 antibody, B7h3 antibody, B7H3 antibody, 4Ig-B7-H3 antibody, B7-H3 antibody, CD276 molecule antibody, CD276 molecule S homeolog antibody, CD276 antigen antibody, Cd276 molecule antibody, CD276 antibody, cd276.S antibody, cd276 antibody, Cd276 antibody
    背景
    B7-H3 is a member of the B7 gene family. It has 88 % amino acid sequence identity with mouse B7-H3. It is mostly expressed on professional APCs, including B cells, macrophages, and dendritic cells. Its expression on dendritic cells appears to be up-regulated by LPS. B7-H3 protein inhibits T cell activation and cytokine production. It was reported that monoclonal antibody against B7-H3 enhanced T cell proliferation in vitro and led to exacerbated EAE in vivo. Therefore, B7-H3 may be a negative regulator on T cell activation and function.
    途径
    Cancer Immune Checkpoints
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