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CD276 抗体

CD276 适用: 人 WB, ELISA, FACS, IHC 宿主: 小鼠 Monoclonal 6A1 unconjugated
产品编号 ABIN969018
发货至: 中国
  • 抗原 See all CD276 抗体
    CD276
    适用
    • 59
    • 37
    • 10
    • 6
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    • 3
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    • 2
    • 1
    宿主
    • 46
    • 15
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    • 1
    小鼠
    克隆类型
    • 39
    • 30
    • 1
    单克隆
    标记
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    • 1
    • 1
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    • 1
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    This CD276 antibody is un-conjugated
    应用范围
    • 51
    • 23
    • 22
    • 14
    • 13
    • 12
    • 9
    • 8
    • 7
    • 6
    • 3
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    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC)
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of human CD276 expressed in E. coli.
    克隆位点
    6A1
    亚型
    IgG1
    Top Product
    Discover our top product CD276 Primary Antibody
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • Zhang, Dong, Xu, Yu, Zhang: "B7-H3: another molecule marker for Mo-DCs?" in: Cellular & molecular immunology, Vol. 2, Issue 4, pp. 307-11, (2005) (PubMed).

    Gerhard, Wagner, Feingold, Shenmen, Grouse, Schuler, Klein, Old, Rasooly, Good, Guyer, Peck, Derge, Lipman, Collins, Jang, Sherry, Feolo, Misquitta, Lee, Rotmistrovsky, Greenhut, Schaefer, Buetow et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, (2004) (PubMed).

  • 抗原
    CD276
    别名
    CD276 (CD276 产品)
    别名
    sc:d0645 antibody, zgc:158279 antibody, 6030411F23Rik antibody, AU016588 antibody, B7RP-2 antibody, B7h3 antibody, B7H3 antibody, 4Ig-B7-H3 antibody, B7-H3 antibody, CD276 molecule antibody, CD276 molecule S homeolog antibody, CD276 antigen antibody, Cd276 molecule antibody, CD276 antibody, cd276.S antibody, cd276 antibody, Cd276 antibody
    背景

    Description: Costimulatory B7 Molecules (e.g., B7-1, or CD80, MIM 112203) signal through CD28 (MIM 186760) family molecules such as CD28, CTLA4 (MIM 123890), and ICOS (MIM 604558). May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. Isoform 2 is shown to enhance the induction of cytotoxic T-cells and selectively stimulates interferon gamma production in the presence of T-cell receptor signaling.

    Aliases: B7H3, B7-H3, 4Ig-B7-H3, CD276

    分子量
    57 kDa
    基因ID
    80381
    HGNC
    80381
    途径
    Cancer Immune Checkpoints
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