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TNFRSF13C 抗体

TNFRSF13C 适用: 人 FACS, IHC 宿主: 小鼠 Monoclonal 11C1 unconjugated
产品编号 ABIN2664463
发货至: 中国
  • 抗原 See all TNFRSF13C 抗体
    TNFRSF13C (Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))
    适用
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    宿主
    • 70
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    小鼠
    克隆类型
    • 69
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    单克隆
    标记
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    This TNFRSF13C antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS), Immunohistochemistry (IHC)
    纯化方法
    The antibody was purified by affinity chromatography.
    克隆位点
    11C1
    亚型
    IgG1 kappa
    Top Product
    Discover our top product TNFRSF13C Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    TNFRSF13C (Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))
    别名
    CD268 (TNFRSF13C 产品)
    别名
    RGD1560810 antibody, TNFRSF13C antibody, BAFF-R antibody, BAFFR antibody, BROMIX antibody, CD268 antibody, CVID4 antibody, prolixin antibody, 2010006P15Rik antibody, Baffr antibody, Bcmd antibody, Bcmd-1 antibody, Bcmd1 antibody, Lvis22 antibody, TNF receptor superfamily member 13C antibody, uncharacterized LOC746611 antibody, tumor necrosis factor receptor superfamily, member 13c antibody, TNFRSF13C antibody, Tnfrsf13c antibody, LOC746611 antibody
    背景
    B cell-activating factor receptor (BAFF-R) is a 19 kD type III membrane protein. It belongs to TNFR superfamily, also known as TNFRSF member 13C (TNFRSF13C), BAFF receptor 3 (BR3), or CD268. BAFF-R is expressed on mature B cells, B cell lymphoma, and T cell subset. BAFF-R is the major receptor for BAFF/BLys (or TALL-1, THANK) which binds to TACI and BCMA as well. The interaction of BAFF with BAFF-R promotes NF-κB activation and plays predominant roles in B-cell maturation and survival as well as costimulates T cell activation and proliferation. TRAF3 is a BAFF-R intracellularly associated protein, which negatively regulates BAFF-R-mediated NF-κB activation.
    途径
    NF-kappaB Signaling
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