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CD276 抗体 (PE)

CD276 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal RTAA15 PE
产品编号 ABIN2663287
发货至: 中国
  • 抗原 See all CD276 抗体
    CD276
    适用
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    小鼠
    宿主
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    大鼠
    克隆类型
    • 39
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    单克隆
    标记
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    This CD276 antibody is conjugated to PE
    应用范围
    • 52
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    Flow Cytometry (FACS)
    纯化方法
    The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
    克隆位点
    RTAA15
    亚型
    IgG2a kappa
    Top Product
    Discover our top product CD276 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.2 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    CD276
    别名
    CD276 (CD276 产品)
    别名
    sc:d0645 antibody, zgc:158279 antibody, 6030411F23Rik antibody, AU016588 antibody, B7RP-2 antibody, B7h3 antibody, B7H3 antibody, 4Ig-B7-H3 antibody, B7-H3 antibody, CD276 molecule antibody, CD276 molecule S homeolog antibody, CD276 antigen antibody, Cd276 molecule antibody, CD276 antibody, cd276.S antibody, cd276 antibody, Cd276 antibody
    背景
    B7-H3 is a member of the B7 gene family. It has 88 % amino acid sequence identity with human B7-H3. It is mostly expressed on professional APCs, including B cells, macrophages, and dendritic cells. Its expression on dendritic cells appears to be up-regulated by LPS. B7-H3 protein inhibits T cell activation and cytokine production. It was reported that monoclonal antibody against B7-H3 enhanced T cell proliferation in vitro and led to exacerbated EAE in vivo. Therefore, B7-H3 may be a negative regulator on T cell activation and function.
    途径
    Cancer Immune Checkpoints
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