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Interleukin 17a 抗体 (FITC)

IL17A 适用: 人 FACS 宿主: 小鼠 Monoclonal BL168 FITC
产品编号 ABIN2661937
发货至: 中国
  • 抗原 See all Interleukin 17a (IL17A) 抗体
    Interleukin 17a (IL17A) (Interleukin 17A (IL17A))
    适用
    • 90
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    宿主
    • 62
    • 40
    • 17
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    小鼠
    克隆类型
    • 71
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    • 1
    单克隆
    标记
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    This Interleukin 17a antibody is conjugated to FITC
    应用范围
    • 71
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    Flow Cytometry (FACS)
    纯化方法
    The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.
    克隆位点
    BL168
    亚型
    IgG1 kappa
    Top Product
    Discover our top product IL17A Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    Interleukin 17a (IL17A) (Interleukin 17A (IL17A))
    别名
    IL-17A (IL17A 产品)
    别名
    CTLA8 antibody, IL-17 antibody, IL-17A antibody, IL17 antibody, Ctla-8 antibody, Ctla8 antibody, Il17 antibody, ChIL-17 antibody, IL-17F antibody, IL17A antibody, CTLA-8 antibody, interleukin 17A antibody, IL17A antibody, Il17a antibody
    背景
    IL-17A is the founding member of the IL-17 family, a group of six structurally related pro-inflammatory cytokines. IL-17A, secreted by activated CD4+ Th17 cell subpopulation, elicits multiple biological activities on a variety of cells including: the induction of IL-6, IL-8, G-CSF, and PGE2 production in epithelial, endothelial or fibroblasts, the enhancement of surface expression of ICAM-1 in fibroblasts, activation of NF-κB and costimulation of T cell proliferation. Recent studies demonstrated that, in mice, activated IL-17-secreting CD4+ helper T cells (Th17 cells) mediate an autoimmune arthritis that clinically and immunologically resembles rheumatoid arthritis (RA). Human IL-17A shows 63 % , 63 %, and 72 % amino acid sequence identity to rat IL-17A, mouse IL-17A, and a protein encoded by the ORF13 gene of herpesvirus Saimiri (HVS), respectively.
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