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Interleukin 17a 抗体

IL17A 适用: 大鼠 ELISA, WB, IHC, Neut, RIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN349633
发货至: 中国
  • 抗原 See all Interleukin 17a (IL17A) 抗体
    Interleukin 17a (IL17A) (Interleukin 17A (IL17A))
    适用
    • 90
    • 42
    • 18
    • 7
    • 6
    • 5
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    • 3
    • 3
    • 3
    • 3
    大鼠
    宿主
    • 61
    • 40
    • 17
    • 7
    • 3
    克隆类型
    • 70
    • 57
    • 1
    多克隆
    标记
    • 62
    • 21
    • 15
    • 10
    • 8
    • 5
    • 1
    • 1
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    This Interleukin 17a antibody is un-conjugated
    应用范围
    • 70
    • 60
    • 31
    • 13
    • 11
    • 11
    • 10
    • 10
    • 8
    • 8
    • 6
    • 5
    • 3
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    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Neutralization (Neut), Radioimmunoassay (RIA)
    交叉反应
    小鼠
    产品特性
    Concentration Definition: by UV absorbance at 280 nm
    免疫原
    This purified antibody was prepared from whole rabbit serum produced by repeated immunizations with full length recombinant rat IL17-A protein.
    Immunogentype:Recombinant
    亚型
    IgG
    Top Product
    Discover our top product IL17A Primary Antibody
  • 应用备注
    This purified antibody has been tested for use in ELISA and western blotting. Reactivity is also expected in neutralizations, radioimmunoassay and immunohistochemistry. The endotoxin content is estimated to be <10 pg/µl by the LAL method. The recombinant immunogen is a non-glycosylated homodimer joined by disulfide bonds having a molecular mass of 30.0 kDa. By western blot from a reducing gel expect a band approximately 15.0 kDa in size corresponding to rat IL17-A protein in the appropriate cell lysate or extract. Specific conditions for reactivity should be optimized by the end user.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Restore with deionized water (or equivalent)
    浓度
    1.0 mg/mL
    缓冲液
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    储存条件
    4 °C
  • Fu, Zhao, Dong, Du, Chen, Wu, Cheng, Du, Liao: "Interleukin-17A contributes to the development of post-operative atrial fibrillation by regulating inflammation and fibrosis in rats with sterile pericarditis." in: International journal of molecular medicine, Vol. 36, Issue 1, pp. 83-92, (2016) (PubMed).

  • 抗原
    Interleukin 17a (IL17A) (Interleukin 17A (IL17A))
    别名
    IL-17A (IL17A 产品)
    别名
    CTLA8 antibody, IL-17 antibody, IL-17A antibody, IL17 antibody, Ctla-8 antibody, Ctla8 antibody, Il17 antibody, ChIL-17 antibody, IL-17F antibody, IL17A antibody, CTLA-8 antibody, interleukin 17A antibody, IL17A antibody, Il17a antibody
    背景
    Rat IL17-A (also known as Interleukin-17, Cytotoxic T-lymphocyte-associated antigen 8 and CTLA-8) is a proinflammatory cytokine member of a six-species family of proteins (IL-17A-17F). Rat IL-17A protein is a homodimer consisting of two 134 amino acids peptides. IL-17A is secreted mainly by activated CD4+ and CD8+ T lymphocytes and acts through its receptor, IL-17R, to induce the expression of many mediators of inflammation, most strikingly, those that are involved in the proliferation, maturation and chemotaxis of neutrophils. Elevated levels of IL-17A have been associated with several conditions, including rheumatoid arthritis, airway inflammation, allograft rejection, inflammatory bowel disease, psoriasis, cancer and multiple sclerosis. There is 58% identity between the amino acid sequence of human and rat IL-17A.
    Synonyms: Interleukin-17, Cytotoxic T-lymphocyte-associated antigen 8 and CTLA-8
    基因ID
    301289
    UniProt
    Q61453
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