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CD14 抗体 (PerCP-Cy5.5)

CD14 适用: 人 FACS, IP, BR 宿主: 小鼠 Monoclonal M5E2 PerCP-Cy5.5
产品编号 ABIN2660275
发货至: 中国
  • 抗原 See all CD14 抗体
    CD14
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    小鼠
    克隆类型
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    单克隆
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    This CD14 antibody is conjugated to PerCP-Cy5.5
    应用范围
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    Flow Cytometry (FACS), Immunoprecipitation (IP), Blocking Reagent (BR)
    交叉反应
    Chimpanzee, Cynomolgus, 猕猴, Capuchin Monkey, Saguinus oedipus, Pigtailed Macaque, Marmoset, Squirrel Monkey (Saimiri spec.), 牛, 猪, 犬
    纯化方法
    The antibody was purified by affinity chromatography, and conjugated with PerCP/Cy5.5 under optimal conditions. The solution is free of unconjugated PerCP/Cy5.5 and unconjugated antibody.
    克隆位点
    M5E2
    亚型
    IgG2a kappa
    Top Product
    Discover our top product CD14 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    CD14
    别名
    CD14 (CD14 产品)
    别名
    CD14 molecule antibody, CD14 antigen antibody, CD14 antibody, Cd14 antibody
    背景
    CD14 is a 53-55 kD glycosylphosphatidylinositol (GPI)-linked membrane glycoprotein also known as LPS receptor. CD14 is expressed at high levels on monocytes and macrophages, and at lower levels on granulocytes. Some dendritic cell populations such as interfollicular dendritic cells, reticular dendritic cells, and Langerhans cells have also been reported to express CD14. As a high-affinity receptor for LPS, CD14 is involved in the clearance of gram-negative pathogens, and in the upregulation of adhesion molecules and expression of cytokines in monocytes and neutrophils.
    途径
    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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