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- 抗原 See all CCR6 抗体
- CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CCR6 antibody is conjugated to PE/Dazzle™ 594
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应用范围
- Flow Cytometry (FACS)
- 交叉反应
- Cynomolgus, 猕猴
- 纯化方法
- The antibody was purified by affinity chromatography and conjugated with PE/Dazzle™ 594 under optimal conditions. The solution is free of unconjugated PE/Dazzle™ 594 and unconjugated antibody.
- 克隆位点
- G034E3
- 亚型
- IgG2b kappa
- Top Product
- Discover our top product CCR6 Primary Antibody
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anti-Chemokine (C-C Motif) Receptor 6 (CCR6) antibody
CCR6 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 7C6D9 unconjugated
anti-Chemokine (C-C Motif) Receptor 6 (CCR6) (AA 201-300) antibodyCCR6 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 6 (CCR6) (N-Term) antibodyCCR6 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 6 (CCR6) antibodyCCR6 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 6 (CCR6) (AA 322-374) antibodyCCR6 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 6 (CCR6) (AA 18-46) antibodyCCR6 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 山羊 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 6 (CCR6) (N-Term) antibodyCCR6 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 6 (CCR6) (AA 18-46) antibodyCCR6 适用: 人, 小鼠 WB, ELISA, IHC, IHC (p) 宿主: 山羊 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Protect from prolonged exposure to light. Do not freeze.
- 储存条件
- 4 °C
- 储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- 抗原
- CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))
- 别名
- CD196 (CCR6 产品)
- 别名
- BN-1 antibody, C-C CKR-6 antibody, CC-CKR-6 antibody, CCR-6 antibody, CD196 antibody, CKR-L3 antibody, CKRL3 antibody, CMKBR6 antibody, DCR2 antibody, DRY6 antibody, GPR29 antibody, GPRCY4 antibody, STRL22 antibody, Cmkbr6 antibody, KY411 antibody, C-C motif chemokine receptor 6 antibody, chemokine (C-C motif) receptor 6 antibody, CCR6 antibody, Ccr6 antibody
- 背景
- CCR6, also known as CD196, is a chemokine receptor that is expressed on immature dendritic cells, B lymphocytes, and memory T cells. CCR6 binds CCL20, although members of the β defensin family also bind CCR6 with a lower affinity. CCR6 positive cells, and its ligand CCL20, have been detected in numerous organs, especially the secondary lymphoid organs. CCL20 is selectively made by the follicle-associated epithelium (FAE) overlying Peyers patches (PPs) and isolated lymphoid follicles (ILFs). CCL20 contributes to the recruitment of CCR6-expressing B cells to these structures. In humans, CCR6 can function to mediate arrest of T cells on dermal endothelial cells and is highly expressed on T cells resident in both normal and psoriatic skin. CCR6 and/or CCL20 have been implicated in the pathogenesis of rheumatoid arthritis and inflammatory bowel disease. Human T cells that are able to produce IL-17 express CCR6. It suggests that CCL20 and CCR6 have a role in inflammatory diseases by recruiting Th17 cells to target tissues.
- 途径
- cAMP Metabolic Process
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