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CCR6 抗体 (AA 18-46)

CCR6 适用: 人, 小鼠 WB, ELISA, IHC, IHC (p) 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN1819417
发货至: 中国
  • 抗原 See all CCR6 抗体
    CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))
    抗原表位
    • 16
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 18-46
    适用
    • 62
    • 28
    • 7
    • 3
    • 2
    • 1
    人, 小鼠
    宿主
    • 49
    • 10
    • 3
    • 2
    山羊
    克隆类型
    • 51
    • 12
    • 1
    多克隆
    标记
    • 30
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CCR6 antibody is un-conjugated
    应用范围
    • 40
    • 24
    • 12
    • 11
    • 11
    • 7
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    Recognizes human CD196, otherwise known as CCR6 (C-C chemokine receptor type 6), a transmembrane glycoprotein and member of the G-protein coupled receptor 1 family, which acts as a specific receptor for the C-C chemokine LARC (Liver and activation-regulated chemokine)/MIP-3alpha, a selective chemoattractant which induces calcium flux in CD196-expressing lymphocytes. CD196 is preferentially expressed by B cells, memory T cells and immature dendritic cells and plays an important role in B lineage maturation and antigen-driven B cell differentiation. CD196 acts as a co-receptor for HIV1 infection, and is selectively expressed by mucosa-associated non-Hodgkin's lymphoma, making the interaction between CD196 and LARC a potential therapeutic target in these malignancies. Cross-reacts with mouse CD196, where linear epitopes are accessible.
    纯化方法
    Affinity purified
    免疫原
    Synthetic peptide YFVSVNTSYYSVDSEMLLCSLQEVRQFSR corresponding to amino acids 18-46 of human CD196. Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon (100%), Chimpanzee (97%), Monkey (86%).

    Type of Immunogen: Synthetic peptide
    亚型
    IgG
    Top Product
    Discover our top product CCR6 Primary Antibody
  • 应用备注
    Approved: ELISA (1:35000), IHC, IHC-P (5 μg/mL), WB (1:250)
    说明

    Target Species of Antibody: Human

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    PBS, 0.1 % sodium azide, 0.1 % BSA
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C,-20 °C
    储存方法
    4°C or -20°C, Avoid freeze-thaw cycles.
  • 抗原
    CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))
    别名
    CCR6 (CCR6 产品)
    别名
    BN-1 antibody, C-C CKR-6 antibody, CC-CKR-6 antibody, CCR-6 antibody, CD196 antibody, CKR-L3 antibody, CKRL3 antibody, CMKBR6 antibody, DCR2 antibody, DRY6 antibody, GPR29 antibody, GPRCY4 antibody, STRL22 antibody, Cmkbr6 antibody, KY411 antibody, C-C motif chemokine receptor 6 antibody, chemokine (C-C motif) receptor 6 antibody, CCR6 antibody, Ccr6 antibody
    背景
    Name/Gene ID: CCR6
    Subfamily: Chemokine
    Family: GPCR

    Synonyms: CCR6, C-c chemokine receptor 6, CD196 antigen, BN-1, C-C chemokine receptor type 6, C-C CKR-6, Chemokine c-c motif receptor 6, CKRL3, CMKBR6, Chemokine (C-C) receptor 6, Chemokine receptor-like 3, Cc chemokine receptor 6, CC-CKR-6, CCR-6, DCR2, DRY6, G protein-coupled receptor 29, DRY-6, G-protein coupled receptor 29, GPR29, GPRCY4, Strl-22, STRL22, CD196, CKR-L3, GPR-CY4, LARC receptor
    基因ID
    1235
    UniProt
    P51684
    途径
    cAMP Metabolic Process
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