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CD45RO 抗体 (PE-Cy7)

CD45RO 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal UCHL1 PE-Cy7
产品编号 ABIN2659283
发货至: 中国
  • 抗原 See all CD45RO products
    CD45RO
    适用
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    宿主
    • 58
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    小鼠
    克隆类型
    • 58
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    单克隆
    标记
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    This CD45RO antibody is conjugated to PE-Cy7
    应用范围
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    Western Blotting (WB), ELISA
    交叉反应
    Chimpanzee, Marmoset
    纯化方法
    The antibody was purified by affinity chromatography and conjugated with PE/Cy7 under optimal conditions. The solution is free of unconjugated PE/Cy7 and unconjugated antibody.
    克隆位点
    UCHL1
    亚型
    IgG2a kappa
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    CD45RO
    别名
    CD45RO (CD45RO 产品)
    背景
    CD45RO is a 180 kD single chain membrane glycoprotein. It is a splice variant of tyrosine phosphatase CD45, lacking the A, B, and C determinants. The CD45RO isoform is expressed on activated and memory T cells, some B cell subsets, activated monocytes/macrophages, and granulocytes. CD45RO enhances both T cell receptor and B cell receptor signaling mediated activation. CD45 and its isoforms non-covalently associate with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1 and CD22. CD45 isoform expression can change in response to cytokines.
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