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- 抗原 See all CD45RO products
- CD45RO
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CD45RO antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人
- 纯化方法
- Purified by Protein A.
- 免疫原
- Cultured T cells from human IL-2-dependent T-cell line (CA1) prepared from human peripheral blood activated with influenza virus.
- 亚型
- IgG
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anti-CD45RO (CD45RO) antibody
GMP Grade CD45RO 适用: 人 FACS, IHC, IP 宿主: 小鼠 Monoclonal UCHL1 unconjugated
anti-CD45RO (CD45RO) antibody (FITC)GMP Grade CD45RO 适用: 人 FACS 宿主: 小鼠 Monoclonal UCHL1 FITC
anti-CD45RO (CD45RO) antibody (PE)GMP Grade CD45RO 适用: 人 FACS 宿主: 小鼠 Monoclonal UCHL1 PE
anti-CD45RO (CD45RO) antibody (mFluor™450)GMP Grade CD45RO 适用: 人 FACS 宿主: 小鼠 Monoclonal UCHL1 mFluor™450
anti-CD45RO (CD45RO) antibody (APC)GMP Grade CD45RO 适用: 人 FACS 宿主: 小鼠 Monoclonal UCHL1 APC
anti-CD45RO (CD45RO) antibody (PE-CF®594)GMP Grade CD45RO 适用: 人 FACS 宿主: 小鼠 Monoclonal UCHL1 PE-CF®594
anti-CD45RO (CD45RO) antibodyCD45RO 适用: 人, Chimpanzee, Marmoset FACS, IF, IHC (p) 宿主: 小鼠 Monoclonal UCHL-1 unconjugated
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- 应用备注
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WB(1:100-500)
Optimal working dilution should be determined by the investigator. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- CD45RO
- 别名
- CD45RO (CD45RO 产品)
- 背景
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Synonyms: B220, CD 45, CD45, cd45 antigen, ec3.1.3.48, CD45R, GP180, GP180, GP 180, L CA, LCA, L-CA, Leukocyte common antigen, LY5, Protein tyrosine phosphatase receptor type C, Protein tyrosine phosphatase receptor type c polypeptide, protein tyrosine phosphatase, receptor type, C, Receptor-type tyrosine-protein phosphatase C, PTPRC, PTPRC_HUMAN, SCID due to PTPRC deficiency, T200, T200 glycoprotein, T200 leukocyte common antigen, Human homolog of severe combined immunodeficiency due to PTPRC deficiency.
Background: CD45RO is a single chain transmembraneous glycoprotein which represents the low molecular weight isoform of the Leucocyte Common Antigen (LCA). It is expressed on most thymocytes, about 45 % of peripheral blood T cells, virtually all T cells in skin reactive infiltrates, and the majority of T cell malignancies. It is also found on a subset of B cells and on exceptional B cell lymphomas.CD45 is a family of single chain transmembraneous glycoproteins consisting of at least four isoforms (220, 205, 190, 180 kDa) which share a common large intracellular domain. Their extracellular domains are heavily glycosylated. The different isoforms are produced by alternative messenger RNA splicing of three exons of a single gene on chromosome 1. CD45 is expressed on cells of the human hematopoietic lineage (including hematopoietic stem cells) with the exception of mature red cells. It is not detected on differentiated cells of other tissues. It is likely that CD45 plays an important role in signal transduction, inhibition or upregulation of various immunological functions. recognising a common epitope on all of the isoforms are termed CD45 whilst those recognising only individual isoforms are termed CD45RA or CD45RO etc.
- 分子量
- 180kDa
- 基因ID
- 5788
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