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H2AFX 抗体 (pSer139) (Alexa Fluor 488)

H2AFX 适用: 人, 小鼠 FACS 宿主: 小鼠 Monoclonal 2F3 Alexa Fluor 488
产品编号 ABIN2657508
发货至: 中国
  • 抗原 See all H2AFX 抗体
    H2AFX (H2A Histone Family, Member X (H2AFX))
    抗原表位
    • 33
    • 26
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    pSer139
    适用
    • 165
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    • 26
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    人, 小鼠
    宿主
    • 148
    • 17
    • 2
    小鼠
    克隆类型
    • 127
    • 40
    单克隆
    标记
    • 107
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    This H2AFX antibody is conjugated to Alexa Fluor 488
    应用范围
    • 132
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    Flow Cytometry (FACS)
    纯化方法
    The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 488 under optimal conditions.
    克隆位点
    2F3
    亚型
    IgG1 kappa
    Top Product
    Discover our top product H2AFX Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C
  • 抗原
    H2AFX (H2A Histone Family, Member X (H2AFX))
    别名
    H2A.X (H2AFX 产品)
    别名
    H2A.X antibody, H2A/X antibody, H2AX antibody, AW228881 antibody, H2ax antibody, Hist5-2ax antibody, gammaH2ax antibody, zgc:56329 antibody, h2a.x antibody, h2a/x antibody, h2ax antibody, RGD1566119 antibody, h2a antibody, h2afx antibody, H2A histone family member X antibody, H2A histone family, member X antibody, H2A histone family member X L homeolog antibody, histone cluster 1, H2ah antibody, histone cluster 2, H2ab S homeolog antibody, histone H2AX antibody, H2AFX antibody, H2afx antibody, h2afx antibody, h2afx.L antibody, HIST1H2AH antibody, hist2h2ab.S antibody, LOC100522201 antibody, LOC100720536 antibody
    背景
    H2A.X is a 14 kD basal histone and a member of the H2 histone family. This nuclear protein is synthesized in the G1 and S phase of the cell cycle and is known to be important for recombination between immunoglobulin switch regions. H2A.X becomes phosphorylated on serine 139 after double-stranded DNA breaks. Phosphorylated H2A.X promotes DNA repair and maintains genomic stability. The 2F3 monoclonal antibody reacts with phosphorylated human H2A.X (Ser139) and has been shown to be useful for Western blotting and immunofluorescence.
    途径
    Telomere Maintenance, DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus
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