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C-JUN 抗体

JUN 适用: 人, 小鼠, 大鼠 WB, IHC (p), IP, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN265356
发货至: 中国
  • 抗原 See all C-JUN (JUN) 抗体
    C-JUN (JUN) (Jun Proto-Oncogene (JUN))
    适用
    • 366
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    • 21
    • 17
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    人, 小鼠, 大鼠
    宿主
    • 360
    • 14
    • 2
    克隆类型
    • 335
    • 41
    多克隆
    标记
    • 186
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    This C-JUN antibody is un-conjugated
    应用范围
    • 256
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)
    特异性
    Antibody detects endogenous levels of AP-1 / c-Jun protein (region surrounding Asn85).
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen
    纯度
    > 95 % pure by SDS-PAGE
    Top Product
    Discover our top product JUN Primary Antibody
  • 应用备注
    ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200. IP: 1: 50approx. 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.2., 0.05 % Sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    C-JUN (JUN) (Jun Proto-Oncogene (JUN))
    别名
    AP-1 / C-Jun (JUN 产品)
    别名
    AP-1 antibody, AP1 antibody, c-Jun antibody, fj36h07 antibody, wu:fj36h07 antibody, zgc:65863 antibody, Junc antibody, c-jun antibody, CG2275 antibody, D-Jun antibody, D-jun antibody, D-jun/Jra antibody, DJUN antibody, DJun antibody, Djun antibody, Dmel\\CG2275 antibody, JRA antibody, JUN antibody, Jun antibody, V antibody, cJun antibody, d-JRA antibody, d-Jun antibody, d-jun antibody, dAP-1 antibody, dJRA antibody, dJUN antibody, dJra antibody, dJun antibody, djun antibody, dm-Jun antibody, jra antibody, jun antibody, l(2)46Ef antibody, l(2)IA109 antibody, l(2R)IA109 antibody, Jun proto-oncogene, AP-1 transcription factor subunit antibody, jun proto-oncogene S homeolog antibody, jun proto-oncogene antibody, Jun-related antigen antibody, jun proto-oncogene L homeolog antibody, JUN antibody, Jun antibody, jun.S antibody, jun antibody, Jra antibody, jun.L antibody
    背景
    The c-Jun proto-oncogene was first identified as the cellular homolog of the avian sarcoma virus v-Jun oncogene. The c-Jun protein, along with c-Fos, is a component of the AP-1 transcriptional complex. c-Jun can form either Jun/Jun homodimers or Jun/Fos heterodimers via the leucine repeats in both proteins. Homo- and heterodimers bind to the TGACTCA consensus sequence present in numerous promoters and initially identified as the phorbol ester tumor promoter response element (TRE). Two additional genes, Jun B and Jun D, have been shown to be almost identical to c-Jun in their C-terminal regions, which are involved in dimerization and DNA binding, whereas their N-terminal domains, which are involved in transcriptional activation, diverge. All three form heterodimers among themselves and with c-Fos and other members of the Fos gene family.Synonyms: Activator protein 1, Proto-oncogene c-jun, Transcription factor AP1, V-jun avian sarcoma virus 17 oncogene homolog, p39
    分子量
    approx. 43, 48 kDa
    基因ID
    3725
    NCBI登录号
    NP_002219
    UniProt
    P05412
    途径
    MAPK Pathway, RTK signaling, WNT signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling, S100 Proteins
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