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CD45 抗体

PTPRC 适用: 人 FACS 宿主: 小鼠 Monoclonal BHKG-2 unconjugated
产品编号 ABIN264270
发货至: 中国
  • 抗原 See all CD45 (PTPRC) 抗体
    CD45 (PTPRC) (Protein tyrosine Phosphatase, Receptor Type, C (PTPRC))
    适用
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CD45 antibody is un-conjugated
    应用范围
    • 441
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    Flow Cytometry (FACS)
    特异性
    CD45RA recognizes Mr. 220-kda of the Leucocyte Common Antigen (LCA).
    产品特性
    Synonyms: Leukocyte common antigen, L-CA, PTPRC, T200, CD45RB, CD45RO, CD45RA, CD45R
    纯化方法
    Purified
    克隆位点
    BHKG-2
    亚型
    IgG1
    Top Product
    Discover our top product PTPRC Primary Antibody
  • 应用备注
    Flow Cytometry. Monitoring of Leucocyte cells subsets in peripheral blood. Characterization of subtypes of leukemias and lymphomas. Studies of AIDS virus infection. Studies of multiple sclerosis and other autoimmune disease.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    实验流程
    PBMC: Add 10 ul of MAB/10e6 PBMC in 100 ul PBS. Mix gently and incubate for 15 minutes at 2-8°C. Wash twice with PBS and analyze or fix with 0. 5% v/v of paraformaldehyde in PBS andanalyze.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.08 % Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store the antibody (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
    Shelf life: One year from despatch.
    有效期
    12 months
  • 抗原
    CD45 (PTPRC) (Protein tyrosine Phosphatase, Receptor Type, C (PTPRC))
    别名
    CD45 / LCA (PTPRC 产品)
    别名
    PTPRC antibody, si:dkeyp-47c5.1 antibody, B220 antibody, CD45 antibody, CD45R antibody, GP180 antibody, L-CA antibody, LCA antibody, LY5 antibody, T200 antibody, Cd45 antibody, Ly-5 antibody, Lyt-4 antibody, loc antibody, Lca antibody, RT7 antibody, cd45 antibody, protein tyrosine phosphatase, receptor type C antibody, protein tyrosine phosphatase, receptor type, C antibody, receptor-type tyrosine-protein phosphatase C antibody, PTPRC antibody, ptprc antibody, LOC100074271 antibody, Ptprc antibody
    背景
    CD45RA antigen is a member of the CD45 antigen family that also includes CD45, CD45RO, and CD45RB antigens. CD45RA is expressed on approximately 75 % of CD8 lymphocytes and 50 % of CD4 lymphocytes, all B cells and NK Cells. CD45RA antigen is expressed on naive T lymphocytes, antigen density decreases upon in vitro activation. A decrease antigen density has been demonstrated for CD4+CD45RA+subset with active multiple sclerosis.Synonyms: L-CA, Leukocyte common antigen, PTPRC, Receptor-type tyrosine-protein phosphatase C, T200
    基因ID
    5788
    UniProt
    P08575
    途径
    TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, CXCR4-mediated Signaling Events, BCR Signaling
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