PIM1 抗体 (pTyr309)
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- 抗原 See all PIM1 抗体
- PIM1 (Pim-1 Oncogene (PIM1))
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抗原表位
- pTyr309
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PIM1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- The antibody detects endogenous levels of Pim-1 only when phosphorylated at tyrosine 309.
- 纯化方法
- Antibodies were purified by affinity-chromatography using epitope-specific peptide.
- 免疫原
- Pim-1 (phospho Tyr309) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 309 (A-A-V (p)-W-S) derived from Human Pim-1.
- 亚型
- IgG
- Top Product
- Discover our top product PIM1 Primary Antibody
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anti-Pim-1 Oncogene (PIM1) (AA 122-261) antibody
PIM1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pim-1 Oncogene (PIM1) (AA 1-100) antibodyPIM1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1C10 unconjugated
anti-Pim-1 Oncogene (PIM1) antibodyPIM1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Pim-1 Oncogene (PIM1) (Internal Region) antibodyPIM1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pim-1 Oncogene (PIM1) (AA 1-100) antibodyPIM1 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 2C9 unconjugated
anti-Pim-1 Oncogene (PIM1) (AA 1-313) antibodyPIM1 适用: 人 ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 3F5 unconjugated
anti-Pim-1 Oncogene (PIM1) (AA 129-268) antibodyPIM1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pim-1 Oncogene (PIM1) (AA 25-86) antibodyPIM1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Pim-1 Oncogene (PIM1) antibodyPIM1 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Pim-1 Oncogene (PIM1) (AA 1-313) antibodyPIM1 适用: 人 ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 6A2 unconjugated
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- 应用备注
- Western Blot: 1:500~1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store antibody at -20°C for up to one year.
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- 抗原
- PIM1 (Pim-1 Oncogene (PIM1))
- 别名
- Pim-1 (PIM1 产品)
- 别名
- PIM antibody, Pim-1 antibody, PIM1 antibody, pim antibody, pim-1 antibody, pim3 antibody, Pim-1 proto-oncogene, serine/threonine kinase antibody, proviral integration site 1 antibody, Pim-1 proto-oncogene, serine/threonine kinase L homeolog antibody, PIM1 antibody, Pim1 antibody, pim1 antibody, pim1.L antibody
- 背景
- Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation and thus providing a selective advantage in tumorigenesis. Exerts its oncogenic activity through: the regulation of MYC transcriptional activity, the regulation of cell cycle progression and by phosphorylation and inhibition of proapoptotic proteins (BAD, MAP3K5, FOXO3). Phosphorylation of MYC leads to an increase of MYC protein stability and thereby an increase of transcriptional activity. The stabilization of MYC exerted by PIM1 might explain partly the strong synergism between these two oncogenes in tumorigenesis.
- 分子量
- 45 kDa
- 基因ID
- 5292
- NCBI登录号
- NP_001230115
- UniProt
- P06803
- 途径
- Glycosaminoglycan Metabolic Process
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