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FAK 抗体 (pSer843)
PTK2
适用: 人, 小鼠, 大鼠
WB
宿主: 兔
Polyclonal
unconjugated
FAK抗体详情
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抗原
See all FAK (PTK2) 抗体
FAK (PTK2)
(PTK2 Protein tyrosine Kinase 2 (PTK2))
抗原表位
All epitopes for FAK 抗体
pSer843
适用
All reactivities for FAK 抗体
人, 小鼠, 大鼠
宿主
All hosts for FAK 抗体
兔
克隆类型
All clonalities for FAK 抗体
多克隆
标记
All conjugates for FAK 抗体
This FAK antibody is un-conjugated
应用范围
All applications for FAK 抗体
Western Blotting (WB)
特异性
The antibody detects endogenous level of FAK only when phosphorylated at serine 843.
纯化方法
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
免疫原
FAK (phospho Ser843) antibody was raised against a peptide sequence around phosphorylation site of serine843 (R-G-S (p)-I-D) derived from Human FAK .
亚型
IgG
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Alternatives
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使用细节
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应用备注
Western Blot: 1:500~1:1000
限制
仅限研究用
贮存及处理
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状态
Liquid
浓度
1 mg/mL
缓冲液
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Store antibody at -20°C for up to one year.
FAK目标详情
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抗原
FAK (PTK2)
(PTK2 Protein tyrosine Kinase 2 (PTK2))
别名
FAK (PTK2 产品 )
别名
FADK antibody, FAK antibody, FAK1 antibody, FRNK antibody, PPP1R71 antibody, p125FAK antibody, pp125FAK antibody, PTK2 antibody, Fadk antibody, mKIAA4203 antibody, fak antibody, fak1a antibody, ptk2 antibody, ptk2a antibody, wu:fa18c04 antibody, zgc:66114 antibody, CG10023 antibody, CT28129 antibody, DFAK antibody, DFak antibody, DFak56 antibody, Dfak antibody, Dfak56 antibody, DmFAK antibody, Dmel\\CG10023 antibody, Fak56 antibody, Fak56D antibody, fak56 antibody, protein tyrosine kinase 2 antibody, protein tyrosine kinase 2 L homeolog antibody, PTK2 protein tyrosine kinase 2 antibody, protein tyrosine kinase 2ab antibody, Focal adhesion kinase antibody, PTK2 antibody, ptk2.L antibody, Ptk2 antibody, ptk2ab antibody, Fak antibody
背景
Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in increased kinase activity.
分子量
120 kDa
基因ID
5747
NCBI登录号
NP_001186578
UniProt
Q05397
途径
Response to Growth Hormone Stimulus , CXCR4-mediated Signaling Events , Smooth Muscle Cell Migration , Signaling of Hepatocyte Growth Factor Receptor , VEGF Signaling
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