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CD40 抗体

CD40 适用: 小鼠, 大鼠 FACS, Func 宿主: 仓鼠 Monoclonal HM40-3 unconjugated
产品编号 ABIN2567686
发货至: 中国
  • 抗原 See all CD40 抗体
    CD40
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    小鼠, 大鼠
    宿主
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    仓鼠
    克隆类型
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    标记
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    This CD40 antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS), Functional Studies (Func)
    特异性
    The HM40-3 monoclonal antibody reacts with mouse CD40, a 48kDA type I glycoprotein known as Bp50.
    纯化方法
    The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.
    克隆位点
    HM40-3
    亚型
    IgM kappa
    Top Product
    Discover our top product CD40 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Phosphate-buffered aqueous solution, ph7.2.
    储存条件
    4 °C
    储存方法
    The product should be stored undiluted at 4°C. Do not freeze.
  • 抗原
    CD40
    别名
    CD40 (CD40 产品)
    别名
    Bp50 antibody, CDW40 antibody, TNFRSF5 antibody, p50 antibody, AI326936 antibody, GP39 antibody, HIGM1 antibody, IGM antibody, IMD3 antibody, T-BAM antibody, TRAP antibody, Tnfrsf5 antibody, TNFSF5 antibody, CD40 molecule antibody, CD40 antigen antibody, CD40 antibody, Cd40 antibody
    背景
    The HM40-3 monoclonal antibody reacts with mouse CD40, a 48kDA type I glycoprotein known as Bp50. CD40 is part of the TNFR family and expressed on a subset of T cells, B cells, dendritic cells, and macrophages. It has been shown to be involved in the protection of B cells from apoptosis, B cell differentiation, co-stimulation, and isotype class-switching. The HM40-3 antibody blocks the binding of CD40L (CD154) and stimulates B and dendritic cell proliferation.
    基因ID
    21939
    UniProt
    P27512
    途径
    NF-kappaB Signaling, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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