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CD40 抗体 (FITC)

CD40 适用: 人 FACS 宿主: 小鼠 Monoclonal 5C3 FITC
产品编号 ABIN2567685
发货至: 中国
  • 抗原 See all CD40 抗体
    CD40
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    小鼠
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    单克隆
    标记
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    This CD40 antibody is conjugated to FITC
    应用范围
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    Flow Cytometry (FACS)
    特异性
    The 5C3 monoclonal antibody specifically reacts with human CD40, a 48kDA type I glycoprotein.
    纯化方法
    The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
    克隆位点
    5C3
    亚型
    IgG1 kappa
    Top Product
    Discover our top product CD40 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
    储存条件
    4 °C
    储存方法
    The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
  • 抗原
    CD40
    别名
    CD40 (CD40 产品)
    别名
    Bp50 antibody, CDW40 antibody, TNFRSF5 antibody, p50 antibody, AI326936 antibody, GP39 antibody, HIGM1 antibody, IGM antibody, IMD3 antibody, T-BAM antibody, TRAP antibody, Tnfrsf5 antibody, TNFSF5 antibody, CD40 molecule antibody, CD40 antigen antibody, CD40 antibody, Cd40 antibody
    背景
    The 5C3 monoclonal antibody specifically reacts with human CD40, a 48kDA type I glycoprotein. CD40 is part of the TNFR family and expressed on a subset of T cells, B cells, dendritic cells, and macrophages. It has been shown to be involved in the protection of B cells from apoptosis, B cell differentiation, co-stimulation, and isotype class-switching. The 5C3 antibody partially blocks the binding of CD40L (CD154). In the presence of IL-4 or PMA, the 5C3 antibody promotes B cell proliferation.
    基因ID
    958
    UniProt
    P25942
    途径
    NF-kappaB Signaling, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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