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HSD11B2 抗体 (AA 181-405)

HSD11B2 适用: 人, 大鼠, 小鸡 WB 宿主: 小鸡 Polyclonal unconjugated
产品编号 ABIN2468177
发货至: 中国
  • 抗原 See all HSD11B2 抗体
    HSD11B2 (Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2))
    抗原表位
    • 19
    • 8
    • 7
    • 6
    • 6
    • 6
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 181-405
    适用
    • 44
    • 24
    • 23
    • 16
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 大鼠, 小鸡
    宿主
    • 63
    • 4
    小鸡
    克隆类型
    • 65
    • 2
    多克隆
    标记
    • 28
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This HSD11B2 antibody is un-conjugated
    应用范围
    • 53
    • 26
    • 19
    • 17
    • 17
    • 12
    • 7
    • 5
    • 4
    • 3
    • 3
    Western Blotting (WB)
    纯化方法
    Immunoaffinity Purified
    Top Product
    Discover our top product HSD11B2 Primary Antibody
  • 应用备注
    Corticosteroid 11-beta-dehydrogenase, isozyme 2 antibody can be used for the detection of Corticosteroid 11-beta-dehydrogenase, isozyme 2 by Western Blot.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Phosphate-Buffered Saline. No preservatives added.
    储存液
    Without preservative
    注意事项
    As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
    储存条件
    4 °C/-20 °C
    储存方法
    HSD11B2 antibody can be stored at 4 °C for short term (weeks). Long term storage should be at -20 °C.
  • 抗原
    HSD11B2 (Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2))
    别名
    HSD11B2 (HSD11B2 产品)
    别名
    MGC81883 antibody, 11-HSD2 antibody, AME antibody, AME1 antibody, HSD11K antibody, HSD2 antibody, SDR9C3 antibody, 11HSD2 antibody, HSD11B2 antibody, hydroxysteroid (11-beta) dehydrogenase 2 L homeolog antibody, hydroxysteroid 11-beta dehydrogenase 2 antibody, hsd11b2.L antibody, HSD11B2 antibody, Hsd11b2 antibody
    背景
    FUNCTION: Catalyzes the conversion of cortisol to the inactive metabolite cortisone. Modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids.

    DISEASE: Defects in HSD11B2 are the cause of apparent mineralocorticoid excess (AME) [MIM:218030]. AME is a potentially fatal disease characterized by severe juvenile low-renin hypertension, sodium retention, hypokalemia and low levels of aldosterone. It often leads to nephrocalcinosis.
    分子量
    44.1 kDa (calculated)
    基因ID
    3291
    NCBI登录号
    NP_000187
    UniProt
    P80365
    途径
    Steroid Hormone Biosynthesis, Regulation of Systemic Arterial Blood Pressure by Hormones
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