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HSD11B2 抗体 (N-Term)

The 兔 多克隆 anti-HSD11B2 antibody is suitable to detect HSD11B2 in samples from 人, 大鼠, 小鼠, Cow, 豚鼠, 兔, 绵羊 和 马. It has been validated for WB.
产品编号 ABIN2776772
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for HSD11B2 抗体 (N-Term) (ABIN2776772)

抗原

See all HSD11B2 抗体
HSD11B2 (Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2))

适用

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人, 大鼠, 小鼠, Cow, 豚鼠, 兔, 绵羊, 马

宿主

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兔

克隆类型

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多克隆

标记

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This HSD11B2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    原理

    HSD11B2 Antibody - N-terminal region

    序列

    ERWPWPSGGA WLLVAARALL QLLRSDLRLG RPLLAALALL AALDWLCQRL

    预测反应

    Cow: 100%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

    产品特性

    This is a rabbit polyclonal antibody against HSD11B2. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human HSD11B2
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41372-100UG

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    prevent freeze-thaw cycles

    储存条件

    4 °C,-20 °C

    储存方法

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    HSD11B2 (Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2))

    别名

    HSD11B2

    背景

    Background Information: HSD11B2 catalyzes the conversion of cortisol to the inactive metabolite cortisone. It modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids.

    Gene Name: Hydroxysteroid (11-beta) dehydrogenase 2

    Alternative Symbols: AME, AME1, HSD2, HSD11K, SDR9C3

    Protein Name: Corticosteroid 11-beta-dehydrogenase isozyme 2

    分子量

    45kDa

    基因ID

    3291

    NCBI登录号

    NP_000187

    UniProt

    P80365

    途径

    Steroid Hormone Biosynthesis, Regulation of Systemic Arterial Blood Pressure by Hormones
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