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HSD11B2 抗体

HSD11B2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7239047
发货至: 中国
  • 抗原 See all HSD11B2 抗体
    HSD11B2 (Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2))
    适用
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    宿主
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    克隆类型
    • 65
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    多克隆
    标记
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    This HSD11B2 antibody is un-conjugated
    应用范围
    • 54
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    ELISA, Immunohistochemistry (IHC)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Synthetic peptide of human HSD11B2
    亚型
    IgG
    Top Product
    Discover our top product HSD11B2 Primary Antibody
  • 应用备注
    IHC 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.6 mg/mL
    缓冲液
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    HSD11B2 (Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2))
    别名
    HSD11B2 (HSD11B2 产品)
    别名
    MGC81883 antibody, 11-HSD2 antibody, AME antibody, AME1 antibody, HSD11K antibody, HSD2 antibody, SDR9C3 antibody, 11HSD2 antibody, HSD11B2 antibody, hydroxysteroid (11-beta) dehydrogenase 2 L homeolog antibody, hydroxysteroid 11-beta dehydrogenase 2 antibody, hsd11b2.L antibody, HSD11B2 antibody, Hsd11b2 antibody
    背景
    There are at least two isozymes of the corticosteroid 11-beta-dehydrogenase, a microsomal enzyme complex responsible for the interconversion of cortisol and cortisone. The type I isozyme has both 11-beta-dehydrogenase (cortisol to cortisone) and 11-oxoreductase (cortisone to cortisol) activities. The type II isozyme, encoded by this gene, has only 11-beta-dehydrogenase activity. In aldosterone-selective epithelial tissues such as the kidney, the type II isozyme catalyzes the glucocorticoid cortisol to the inactive metabolite cortisone, thus preventing illicit activation of the mineralocorticoid receptor.
    NCBI登录号
    NP_000187
    UniProt
    P80365
    途径
    Steroid Hormone Biosynthesis, Regulation of Systemic Arterial Blood Pressure by Hormones
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