MDM4-binding Protein 抗体
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- 抗原 See all MDM4-binding Protein (MDM4) 抗体
- MDM4-binding Protein (MDM4) (Mdm4-binding Protein (MDM4))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MDM4-binding Protein antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 纯化方法
- Antibody is purified by protein A chromatography method.
- 免疫原
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MDM4.
- Top Product
- Discover our top product MDM4 Primary Antibody
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anti-Mdm4-binding Protein (MDM4) (AA 1-490) antibody
MDM4 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Mdm4-binding Protein (MDM4) antibodyMDM4 适用: 人 WB, ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 2D10F4 unconjugated
anti-Mdm4-binding Protein (MDM4) antibodyMDM4 适用: 人 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 2D11 unconjugated
anti-Mdm4-binding Protein (MDM4) (AA 1-490) antibodyMDM4 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Mdm4-binding Protein (MDM4) antibodyMDM4 适用: 人 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 3A6 unconjugated
anti-Mdm4-binding Protein (MDM4) (pSer367) antibodyMDM4 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mdm4-binding Protein (MDM4) (AA 130-179) antibodyMDM4 适用: 人, Cow, Pig, 兔 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Mdm4-binding Protein (MDM4) (N-Term) antibodyMDM4 适用: 人, Cow, Pig, 兔, 犬, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Mdm4-binding Protein (MDM4) (AA 301-400) antibodyMDM4 适用: 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Mdm4-binding Protein (MDM4) (AA 208-306) antibodyMDM4 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- MDM4 antibody can be used for detection of MDM4 by ELISA at 1:62500. MDM4 antibody can be used for detection of MDM4 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- 浓度
- 1 mg/mL
- 缓冲液
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- 注意事项
- As with any antibody avoid repeat freeze-thaw cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store MDM4 antibody at -20 °C.
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- 抗原
- MDM4-binding Protein (MDM4) (Mdm4-binding Protein (MDM4))
- 别名
- MDM4 (MDM4 产品)
- 别名
- mdmx antibody, HDMX antibody, MDMX antibody, MRP1 antibody, wu:fa09h09 antibody, wu:fi33d10 antibody, 4933417N07Rik antibody, AA414968 antibody, AL023055 antibody, AU018793 antibody, AU021806 antibody, C85810 antibody, Mdmx antibody, MDM4, p53 regulator S homeolog antibody, MDM4, p53 regulator antibody, transformed mouse 3T3 cell double minute 4 antibody, mdm4.S antibody, MDM4 antibody, Mdm4 antibody, mdm4 antibody
- 背景
- MDM4 inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. inhibits degradation of MDM2. It can reverse MDM2-targeted degradation of p53 while maintaining suppression of p53 transactivation and apoptotic functions.The human MDM4 gene, which plays a role in apoptosis, encodes a 490-amino acid protein containing a RING finger domain and a putative nuclear localization signal. The MDM4 putative nuclear localization signal, which all Mdm proteins contain, is located in the C-terminal region of the protein. The mRNA is expressed at a high level in thymus and at lower levels in all other tissues tested. MDM4 protein produced by in vitro translation interacts with p53 via a binding domain located in the N-terminal region of the MDM4 protein. MDM4 shows significant structural similarity to p53-binding protein MDM2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
- 分子量
- 55 kDa
- 基因ID
- 4194
- NCBI登录号
- NP_002384
- UniProt
- O15151
- 途径
- Cell Division Cycle
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