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SSRP1 抗体

SSRP1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2461682
发货至: 中国
  • 抗原 See all SSRP1 抗体
    SSRP1 (Structure Specific Recognition Protein 1 (SSRP1))
    适用
    • 61
    • 20
    • 16
    • 8
    • 4
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 56
    • 4
    • 1
    克隆类型
    • 57
    • 4
    多克隆
    标记
    • 34
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This SSRP1 antibody is un-conjugated
    应用范围
    • 44
    • 20
    • 10
    • 9
    • 8
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    纯化方法
    Antibody is purified by peptide affinity chromatography method.
    免疫原
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SSRP1.
    Top Product
    Discover our top product SSRP1 Primary Antibody
  • 应用备注
    SSRP1 antibody can be used for detection of SSRP1 by ELISA at 1:1562500. SSRP1 antibody can be used for detection of SSRP1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    浓度
    1 mg/mL
    缓冲液
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    注意事项
    As with any antibody avoid repeat freeze-thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store SSRP1 antibody at -20 °C.
  • 抗原
    SSRP1 (Structure Specific Recognition Protein 1 (SSRP1))
    别名
    SSRP1 (SSRP1 产品)
    别名
    ATHMG antibody, NFD antibody, NUCLEOSOME/CHROMATIN ASSEMBLY FACTOR D antibody, SSRP1 antibody, high mobility group antibody, ssrp1 antibody, CG4817 antibody, Cf5 antibody, Dmel\\CG4817 antibody, DssRP antibody, SSRP antibody, dSSRP antibody, dSSRP1 antibody, dSsrp antibody, ssrp antibody, Ssrp1 antibody, DDBDRAFT_0188842 antibody, DDBDRAFT_0216434 antibody, DDB_0188842 antibody, DDB_0216434 antibody, wu:fa11b03 antibody, wu:fd10f06 antibody, FACT antibody, FACT80 antibody, T160 antibody, CIIDBP antibody, C81323 antibody, Hmg1-rs1 antibody, Hmgi-rs3 antibody, Hmgox antibody, high mobility group antibody, FACT complex subunit Ssrp1 antibody, FACT complex subunit SSRP1 antibody, Structure specific recognition protein antibody, structure specific recognition protein 1 antibody, transcription factor protein antibody, structure specific recognition protein 1a antibody, SSRP1 protein antibody, structure specific recognition protein 1 S homeolog antibody, HMG antibody, CpipJ_CPIJ002953 antibody, CpipJ_CPIJ020011 antibody, CMU_019430 antibody, Tsp_07406 antibody, LOC100286423 antibody, Ssrp antibody, ssrp1 antibody, SSRP1 antibody, ssrp1a antibody, nfd110 antibody, ssrp1.S antibody, Ssrp1 antibody
    背景
    SSRP1 is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. SSRP1 contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. It also functions as a co-activator of the transcriptional activator p63.The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    分子量
    81 kDa
    基因ID
    6749
    NCBI登录号
    NP_003137
    UniProt
    Q08945
    途径
    Chromatin Binding
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