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SSRP1 抗体

KO Validated SSRP1 适用: 人 WB, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2856824
发货至: 中国
  • 抗原 See all SSRP1 抗体
    SSRP1 (Structure Specific Recognition Protein 1 (SSRP1))
    适用
    • 62
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    • 1
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    宿主
    • 57
    • 4
    • 1
    克隆类型
    • 58
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    多克隆
    标记
    • 35
    • 4
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    • 3
    • 2
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    This SSRP1 antibody is un-conjugated
    应用范围
    • 45
    • 20
    • 10
    • 9
    • 8
    • 2
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    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    Knockdown/Knockout validation was supported by references (PMID:26990993)
    交叉反应
    产品特性
    Rabbit polyclonal antibody to SSRP1 (structure specific recognition protein 1)
    SSRP1 antibody [N1N3]
    纯化方法
    Purified by antigen-affinity chromatography.
    质量等级
    KO Validated
    免疫原
    Recombinant protein encompassing a sequence within the center region of human SSRP1. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product SSRP1 Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: Molt-4 , 293T , A431 , HeLa , HepG2 , Jurkat

    Validation: KO/KD

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    SSRP1 (Structure Specific Recognition Protein 1 (SSRP1))
    别名
    structure specific recognition protein 1 (SSRP1 产品)
    别名
    ATHMG antibody, NFD antibody, NUCLEOSOME/CHROMATIN ASSEMBLY FACTOR D antibody, SSRP1 antibody, high mobility group antibody, ssrp1 antibody, CG4817 antibody, Cf5 antibody, Dmel\\CG4817 antibody, DssRP antibody, SSRP antibody, dSSRP antibody, dSSRP1 antibody, dSsrp antibody, ssrp antibody, Ssrp1 antibody, DDBDRAFT_0188842 antibody, DDBDRAFT_0216434 antibody, DDB_0188842 antibody, DDB_0216434 antibody, wu:fa11b03 antibody, wu:fd10f06 antibody, FACT antibody, FACT80 antibody, T160 antibody, CIIDBP antibody, C81323 antibody, Hmg1-rs1 antibody, Hmgi-rs3 antibody, Hmgox antibody, high mobility group antibody, FACT complex subunit Ssrp1 antibody, FACT complex subunit SSRP1 antibody, Structure specific recognition protein antibody, structure specific recognition protein 1 antibody, transcription factor protein antibody, structure specific recognition protein 1a antibody, SSRP1 protein antibody, structure specific recognition protein 1 S homeolog antibody, HMG antibody, CpipJ_CPIJ002953 antibody, CpipJ_CPIJ020011 antibody, CMU_019430 antibody, Tsp_07406 antibody, LOC100286423 antibody, Ssrp antibody, ssrp1 antibody, SSRP1 antibody, ssrp1a antibody, nfd110 antibody, ssrp1.S antibody, Ssrp1 antibody
    背景
    The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known.

    Cellular Localization: Nucleus
    分子量
    81 kDa
    基因ID
    6749
    UniProt
    Q08945
    途径
    Chromatin Binding
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