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NCOR2 抗体

NCOR2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2460475
发货至: 中国
  • 抗原 See all NCOR2 抗体
    NCOR2 (Nuclear Receptor Co-Repressor 2 (NCOR2))
    适用
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    宿主
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    克隆类型
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    多克隆
    标记
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    This NCOR2 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), ELISA
    纯化方法
    Antibody is purified by peptide affinity chromatography method.
    免疫原
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NCOR2.
    Top Product
    Discover our top product NCOR2 Primary Antibody
  • 应用备注
    NCOR2 antibody can be used for detection of NCOR2 by ELISA at 1:12500. NCOR2 antibody can be used for detection of NCOR2 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    浓度
    1 mg/mL
    缓冲液
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    注意事项
    As with any antibody avoid repeat freeze-thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store NCOR2 antibody at -20 °C.
  • 抗原
    NCOR2 (Nuclear Receptor Co-Repressor 2 (NCOR2))
    别名
    NCOR2 (NCOR2 产品)
    别名
    CTG26 antibody, N-CoR2 antibody, SMAP270 antibody, SMRT antibody, SMRTE antibody, SMRTE-tau antibody, TNRC14 antibody, TRAC antibody, TRAC-1 antibody, TRAC1 antibody, N-CoR antibody, SMRTe antibody, NCOR2 antibody, gb:be017685 antibody, si:bz71m17.2 antibody, smrt antibody, ctg26 antibody, smrte antibody, trac1 antibody, tnrc14 antibody, trac-1 antibody, smrte-tau antibody, nuclear receptor corepressor 2 antibody, nuclear receptor co-repressor 2 antibody, NCOR2 antibody, Ncor2 antibody, ncor2 antibody
    背景
    NCOR2 forms a large corepressor complex that contains SIN3A/B and histone deacetylases HDAC1 and HDAC2. This complex associates with the thyroid (TR) and the retinoid acid receptors (RAR) in the absence of ligand, and may stabilize their interaction with TFIIB. NCOR2 mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription.Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.
    分子量
    275 kDa
    基因ID
    9612
    NCBI登录号
    NP_006303
    UniProt
    Q9Y618
    途径
    Notch Signaling, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
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