NCOR2 抗体 (AA 511-560)
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北京 101111
Quick Overview for NCOR2 抗体 (AA 511-560) (ABIN1534223)
抗原
See all NCOR2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 511-560
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原理
- SMRTe Antibody
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特异性
- SMRTe Polyclonal Antibody detects endogenous levels of SMRTe protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human NCOR2. AA range:511-560
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亚型
- IgG
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应用备注
- WB 1:500-2000 IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- NCOR2 (Nuclear Receptor Co-Repressor 2 (NCOR2))
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别名
- NCOR2
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背景
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Synonyms: NCOR2, CTG26, Nuclear receptor corepressor 2, N-CoR2, CTG repeat protein 26, SMAP270, Silencing mediator of retinoic acid and thyroid hormone receptor, SMRT, T3 receptor-associating factor, TRAC, Thyroid-, retinoic-acid-receptor-associated
Background: This gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of this gene is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Apr 2011],
Gene Name: NCOR2
Protein Name: Nuclear receptor corepressor 2
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分子量
- 274 kDa
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基因ID
- 9612
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OMIM
- 600848
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UniProt
- Q9Y618
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途径
- Notch Signaling, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
抗原
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