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NCOR2 抗体 (AA 511-560)

The 兔 多克隆 anti-NCOR2 antibody is suitable to detect NCOR2 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, ELISA, IF 和 IHC.
产品编号 ABIN1534223
发货至: 中国
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Quick Overview for NCOR2 抗体 (AA 511-560) (ABIN1534223)

抗原

See all NCOR2 抗体
NCOR2 (Nuclear Receptor Co-Repressor 2 (NCOR2))

适用

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人, 小鼠, 大鼠

宿主

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兔

克隆类型

  • 63
  • 5
多克隆

标记

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This NCOR2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)
  • 抗原表位

    • 15
    • 13
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    AA 511-560

    原理

    SMRTe Antibody

    特异性

    SMRTe Polyclonal Antibody detects endogenous levels of SMRTe protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human NCOR2. AA range:511-560

    亚型

    IgG
  • 应用备注

    WB 1:500-2000 IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    NCOR2 (Nuclear Receptor Co-Repressor 2 (NCOR2))

    别名

    NCOR2

    背景

    Synonyms: NCOR2, CTG26, Nuclear receptor corepressor 2, N-CoR2, CTG repeat protein 26, SMAP270, Silencing mediator of retinoic acid and thyroid hormone receptor, SMRT, T3 receptor-associating factor, TRAC, Thyroid-, retinoic-acid-receptor-associated

    Background: This gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of this gene is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Apr 2011],

    Gene Name: NCOR2

    Protein Name: Nuclear receptor corepressor 2

    分子量

    274 kDa

    基因ID

    9612

    OMIM

    600848

    UniProt

    Q9Y618

    途径

    Notch Signaling, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
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