LRRC8A antibody can be used for detection of LRRC8A by ELISA at 1:62500. LRRC8A antibody can be used for detection of LRRC8A by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
浓度
1 mg/mL
缓冲液
Antibody is lyophilized in PBS buffer with 2 % sucrose.
注意事项
As with any antibody avoid repeat freeze-thaw cycles.
储存条件
4 °C/-20 °C
储存方法
For short periods of storage (days) store at 4 °C. For longer periods of storage, store LRRC8A antibody at -20 °C.
抗原
LRRC8A
(Leucine Rich Repeat Containing 8 Family, Member A (LRRC8A))
AGM5 antibody, LRRC8 antibody, Lrrc8 antibody, mKIAA1437 antibody, wu:fb18g12 antibody, wu:fi21b10 antibody, LLRC8A antibody, leucine rich repeat containing 8 VRAC subunit A antibody, leucine rich repeat containing 8A antibody, leucine rich repeat containing 8 VRAC subunit Aa antibody, leucine-rich repeat containing 8 family member A S homeolog antibody, leucine rich repeat containing 8 family member A antibody, LRRC8A antibody, Lrrc8a antibody, lrrc8aa antibody, lrrc8a.S antibody
背景
LRRC8A is a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. LRRC8A is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. This gene encodes a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. This family member is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.