LRRC8A 抗体 (N-Term)
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北京 101111
Quick Overview for LRRC8A 抗体 (N-Term) (ABIN2783752)
抗原
See all LRRC8A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- LRRC8A Antibody - N-terminal region
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序列
- IPVTELRYFA DTQPAYRILK PWWDVFTDYI SIVMLMIAVF GGTLQVTQDK
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against LRRC8A. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human LRRC8A
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anti-Leucine Rich Repeat Containing 8 Family, Member A (LRRC8A) (1st Extracellular Loop), (AA 91-104) antibody
LRRC8A 适用: 人 WB, FACS, IF, LCI 宿主: 兔 Polyclonal unconjugated
anti-Leucine Rich Repeat Containing 8 Family, Member A (LRRC8A) (AA 782-810), (C-Term) antibodyLRRC8A 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB30632 unconjugated
anti-Leucine Rich Repeat Containing 8 Family, Member A (LRRC8A) (AA 711-810) antibodyLRRC8A 适用: 人 WB 宿主: 小鼠 Monoclonal 8H9 unconjugated
anti-Leucine Rich Repeat Containing 8 Family, Member A (LRRC8A) (N-Term) antibodyLRRC8A 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼, Bat, 猴, Pig, 小鸡, Hamster, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Leucine Rich Repeat Containing 8 Family, Member A (LRRC8A) (C-Term) antibodyLRRC8A 适用: 人, Cow, 犬, 豚鼠, 马, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Leucine Rich Repeat Containing 8 Family, Member A (LRRC8A) (AA 760-810) antibodyLRRC8A 适用: 人, 小鼠 WB, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP49452-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- LRRC8A (Leucine Rich Repeat Containing 8 Family, Member A (LRRC8A))
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别名
- LRRC8A
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背景
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Background Information: LRRC8A is a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. LRRC8A is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. This gene encodes a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. This family member is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.
Gene Name: Leucine rich repeat containing 8 family, member A
Alternative Symbols: AGM5, LRRC8, SWELL1, HsLRRC8A
Protein Name: Leucine-rich repeat-containing protein 8A
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分子量
- 94kDa
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基因ID
- 56262
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NCBI登录号
- NP_062540
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UniProt
- Q8IWT6
抗原
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