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LRRC8A 抗体 (C-Term)

LRRC8A 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB30632 unconjugated
产品编号 ABIN1881512
发货至: 中国
  • 抗原 See all LRRC8A 抗体
    LRRC8A (Leucine Rich Repeat Containing 8 Family, Member A (LRRC8A))
    抗原表位
    • 13
    • 7
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 782-810, C-Term
    适用
    • 21
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 20
    • 1
    克隆类型
    • 20
    • 1
    多克隆
    标记
    • 11
    • 2
    • 2
    • 2
    • 2
    • 2
    This LRRC8A antibody is un-conjugated
    应用范围
    • 21
    • 15
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    预测反应
    Rat
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This LRRC8A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 782-810 amino acids from the C-terminal region of human LRRC8A.
    克隆位点
    RB30632
    亚型
    Ig Fraction
    Top Product
    Discover our top product LRRC8A Primary Antibody
  • 应用备注
    WB: 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Smits, Kajava: "LRRC8 extracellular domain is composed of 17 leucine-rich repeats." in: Molecular immunology, Vol. 41, Issue 5, pp. 561-2, (2004) (PubMed).

    Conley: "Genes required for B cell development." in: The Journal of clinical investigation, Vol. 112, Issue 11, pp. 1636-8, (2003) (PubMed).

  • 抗原
    LRRC8A (Leucine Rich Repeat Containing 8 Family, Member A (LRRC8A))
    别名
    LRRC8A (LRRC8A 产品)
    别名
    AGM5 antibody, LRRC8 antibody, Lrrc8 antibody, mKIAA1437 antibody, wu:fb18g12 antibody, wu:fi21b10 antibody, LLRC8A antibody, leucine rich repeat containing 8 VRAC subunit A antibody, leucine rich repeat containing 8A antibody, leucine rich repeat containing 8 VRAC subunit Aa antibody, leucine-rich repeat containing 8 family member A S homeolog antibody, leucine rich repeat containing 8 family member A antibody, LRRC8A antibody, Lrrc8a antibody, lrrc8aa antibody, lrrc8a.S antibody
    背景
    This gene encodes a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. This family member is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.
    分子量
    94199
    NCBI登录号
    NP_001120716, NP_001120717, NP_062540
    UniProt
    Q8IWT6
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