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Nephrin 抗体

NPHS1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2426273
发货至: 中国
  • 抗原 See all Nephrin (NPHS1) 抗体
    Nephrin (NPHS1) (Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1))
    适用
    • 80
    • 49
    • 28
    • 15
    人, 小鼠, 大鼠
    宿主
    • 82
    • 5
    • 2
    • 1
    克隆类型
    • 81
    • 9
    多克隆
    标记
    • 38
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    • 4
    • 4
    • 3
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    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Nephrin antibody is un-conjugated
    应用范围
    • 39
    • 37
    • 19
    • 18
    • 16
    • 11
    • 9
    • 8
    • 7
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    纯化方法
    Affinity purification
    免疫原
    Synthetic peptide of human NPHS1
    亚型
    IgG
    Top Product
    Discover our top product NPHS1 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:25-1:100
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/mL
    缓冲液
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    储存液
    Sodium azide
    注意事项
    Avoid freeze / thaw cycles.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    Nephrin (NPHS1) (Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1))
    别名
    NPHS1 (NPHS1 产品)
    别名
    NPHS1 antibody, nphs1l antibody, nphs1 antibody, CNF antibody, NPHN antibody, nephrin antibody, NephrinB antibody, NPHS1, nephrin antibody, nephrosis 1, congenital, Finnish type (nephrin) antibody, NPHS1 nephrin S homeolog antibody, nephrin antibody, NPHS1 nephrin antibody, nephrosis 1, nephrin antibody, NPHS1 antibody, nphs1 antibody, nphs1.S antibody, LOC5579127 antibody, Nphs1 antibody
    背景
    CNF,Nephrin,Nephrosis 1 congenital Finnish type,Nephrosis 1,congenital,Finnish type (nephrin),NPHN,NPHN,NPHS 1,Nphs1,Renal glomerulus specific cell adhesion receptor,Renal glomerulus-specific cell adhesion receptor,This gene encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. The gene is primarily expressed in renal tissues, and the protein is a type-1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this gene result in Finnish-type congenital nephrosis 1, characterized by severe proteinuria and loss of the slit diaphragm and foot processes.In Western blots, nephrin antibodies generated against the two terminal extracellular Ig domains of recombinant human nephrin recognized a 180- kDa protein in lysates of human glomeruli and a 150- kDa protein in transfected COS-7 cell lysates.
    分子量
    Calculated MW: 135 kDa
    NCBI登录号
    NP_004637
    途径
    Regulation of Actin Filament Polymerization, Skeletal Muscle Fiber Development
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