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HLA-DRB1 抗体

HLA-DRB1 适用: 人 WB, FACS, EIA 宿主: 小鼠 Monoclonal MEM-267 unconjugated
产品编号 ABIN238469
发货至: 中国
  • 抗原 See all HLA-DRB1 抗体
    HLA-DRB1 (Major Histocompatibility Complex, Class II, DR beta 1 (HLA-DRB1))
    适用
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    宿主
    • 54
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    小鼠
    克隆类型
    • 53
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    单克隆
    标记
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    This HLA-DRB1 antibody is un-conjugated
    应用范围
    • 61
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    Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
    产品特性
    Synonyms: MHC class II antigen DRB1, DR1, DR-1, HLA class II histocompatibility antigen, DRB1-1 betachain
    纯化方法
    Protein A affinity chromatography.
    免疫原
    Purified, insoluble DR1 beta chain (DRB1*0101) expressed in E. coli inclusion bodies.
    克隆位点
    MEM-267
    亚型
    IgG2b
    Top Product
    Discover our top product HLA-DRB1 Primary Antibody
  • 应用备注
    Western Blotting. Flow Cytometry: The antibody MEM-267 stains immature dendritic cells that express emptycell surface MHC molecules, but not cells that express predominantly peptide loadedforms. ELISA.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS, pH 7.4 containing 15 mM sodium azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    HLA-DRB1 (Major Histocompatibility Complex, Class II, DR beta 1 (HLA-DRB1))
    别名
    HLA Class II DR beta 1 / HLA-DRB1 (HLA-DRB1 产品)
    别名
    MGC108235 antibody, DRB1 antibody, DRw10 antibody, HLA-DR1B antibody, HLA-DRB antibody, SS1 antibody, major histocompatibility complex, class II, DR beta 1 antibody, hla-drb1 antibody, HLA-DRB1 antibody
    背景
    HLA-DR1 belongs to the HLA class II beta chain paralogues. The MHC Class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. MHC Class II molecules are expressed in antigen presenting cells (APC). The beta chain is approximately 26-28 kDa. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Hundreds of DRB1 alleles have been described and typing for these polymorphisms is routinely done for bone marrow and kidney transplantation.Synonyms: DR-1, DR1, DRB1-1 beta chain, HLA class II histocompatibility antigen, MHC class II antigen DRB1
    UniProt
    P04229
    途径
    TCR Signaling, Positive Regulation of Peptide Hormone Secretion, Production of Molecular Mediator of Immune Response, CXCR4-mediated Signaling Events, Cancer Immune Checkpoints
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